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| Catalog Number | Size | Price |
|---|---|---|
| LS-C389447-7 | 7 ml | $574 |
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Monoclonal Mouse anti‑Human BCL2 / Bcl‑2 Antibody (clone 100/D5 + 124, Ready‑to‑Use, aa41‑54, IHC, IF, WB) LS‑C389447
Monoclonal Mouse anti‑Human BCL2 / Bcl‑2 Antibody (clone 100/D5 + 124, Ready‑to‑Use, aa41‑54, IHC, IF, WB) LS‑C389447
Antibody:
BCL2 / Bcl-2 Mouse anti-Human Monoclonal (aa41-54) (Ready-to-Use) (100/D5 + 124) Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo
Reactivity:
Human, Chimpanzee, Dog, Pig
Format:
Unconjugated, Ready-to-Use
Other formats:
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
BCL2 / Bcl-2 Mouse anti-Human Monoclonal (aa41-54) (Ready-to-Use) (100/D5 + 124) Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo
Reactivity:
Human, Chimpanzee, Dog, Pig
Format:
Unconjugated, Ready-to-Use
Other formats:
Specifications
Description
Bcl-2 antibody LS-C389447 is an unconjugated mouse monoclonal antibody to Bcl-2 (BCL2) (aa41-54) from human. It is reactive with human, chimpanzee, dog and other species. Validated for Flow, IF, IHC, IP and WB.
Target
Human BCL2 / Bcl-2
Synonyms
BCL2 | Apoptosis regulator Bcl-2 | B-cell CLL/lymphoma 2 | B-cell lymphoma protein 2 | Bcl-2 | PPP1R50
Host
Mouse
Reactivity
Human, Chimpanzee, Dog, Pig
(tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat
Clonality
IgG1,k
Monoclonal
Clone
100/D5 + 124
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Ready-to-Use.
Also available Unmodified or Azide-free, BSA-free.
Immunogen
A synthetic peptide, aa 41-54 (G aa PAPGIFSSQPG) of the human protein. Percent identity by BLAST analysis: Human, Chimpanzee, Cat, Pig, Dog (100%); Gorilla, Orangutan, Bovine, Goat (91%); Galago (82%).
Epitope
aa41-54
Specificity
Human BCL2 / Bcl-2
Applications
- IHC
- IHC - Paraffin (1:1)
- Immunofluorescence
- Western blot
- Immunoprecipitation
- Flow Cytometry
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. B-cell lymphoma 2 is an oncogene that regulates apoptosis, having both inducing and inhibiting functions. In cancer cells, Bcl2 binds pro-apoptotic proteins, preventing programmed cell death from occurring. Overexpression is seen in many cancers including lung, breast, prostate and lymphomas. In most follicular lymphomas, neoplastic germinal centers express high levels of the protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, Bcl2 antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BCL2 / Bcl-2
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Immunoprecipitation
Species:
Mouse, Rat
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Species:
Human, Monkey, Dog, Pig
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Species:
Human, Mouse, Rat, Dog
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
