BBS5

Bardet-Biedl syndrome 5

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.

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Antibodies (15)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (15)

Recombinant (1)

Target

BBS5 (18)

Reactivity

Human (15)

Mouse (7)

Rat (7)

Bovine (3)

Chicken (3)

Chimpanzee (6)

Dog (6)

Gibbon (6)

Guinea pig (6)

Horse (6)

Monkey (6)

Pig (6)

Rabbit (6)

Xenopus (3)

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IHC (2)

WB (15)

ELISA (2)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (13)

mouse (2)

Isotype

IgG (9)

IgG2a (1)

Clonality

monoclonal mc (1)

polyclonal pc (14)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (9)

Epitope

C-Terminus (4)

N-Terminus (4)

aa108-141 (1)

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No (18)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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BBS5 Antibody LS-C659833

Antibody:

BBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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BBS5 Antibody LS-C808873

Antibody:

BBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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BBS5 Antibody LS-C659837

Antibody:

BBS5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$351

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BBS5 Antibody LS-C747772

Antibody:

BBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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BBS5 Antibody (N-Terminus) LS-C135010

Antibody:

BBS5 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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BBS5 Antibody (N-Terminus, HRP) LS-C456810

Antibody:

BBS5 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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BBS5 Antibody (N-Terminus, Biotin) LS-C456807

Antibody:

BBS5 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

BBS5 Antibody (N-Terminus, FITC) LS-C456808

Antibody:

BBS5 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BBS5 Antibody (C-Terminus) LS-C102493

Antibody:

BBS5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

BBS5 Antibody (C-Terminus, HRP) LS-C456812

Antibody:

BBS5 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

BBS5 Antibody (C-Terminus, Biotin) LS-C456809

Antibody:

BBS5 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

BBS5 Antibody (C-Terminus, FITC) LS-C456811

Antibody:

BBS5 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BBS5 Antibody (aa108-141) LS-C344202

Antibody:

BBS5 Rabbit anti-Human Polyclonal (aa108-141) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

BBS5 Antibody LS-C832995

Antibody:

BBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

BBS5 Antibody LS-C306509

Antibody:

BBS5 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

Select

Human BBS5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93609

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.6 kDa

Price:

20 µg/$150

Select

Human BBS5 Protein (Recombinant GST) (Full Length) - LS-G36455

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

65.2 kDa

Price:

10 µg/$479; 25 µg/$670

Select

BBS5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102348

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.6 kDa

Price:

100 µg/$494

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