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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-C391916-7 7 ml $465 
Basic Cytokeratin Antibody - IHC testing of FFPE rat stomach with Basic Cytokeratin antibody (clone BCCK1-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Basic Cytokeratin Antibody - IHC testing of FFPE human breast carcinoma with Basic Cytokeratin antibody (clone BCCK1-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Basic Cytokeratin Antibody - IHC testing of FFPE rat stomach with Basic Cytokeratin antibody (clone BCCK1-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Basic Cytokeratin Antibody - IHC testing of FFPE human breast carcinoma with Basic Cytokeratin antibody (clone BCCK1-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Basic Cytokeratin Antibody (clone BCCK1‑1, Ready‑to‑Use) LS‑C391916

Basic Cytokeratin Antibody (clone BCCK1‑1, Ready‑to‑Use) LS‑C391916

Antibody:
Mouse Monoclonal to Human Basic Cytokeratin
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human, Rat
Format:
Unconjugated, Ready-to-Use
Other formats:
Price
Catalog Number
$465 
LS-C391916-7
7 ml
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human Basic Cytokeratin
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human, Rat
Format:
Unconjugated, Ready-to-Use
Other formats:

Specifications

Description
Basic Cytokeratin antibody LS-C391916 is an unconjugated mouse monoclonal antibody to Basic Cytokeratin from human and rat. Validated for IF, IHC and WB.
Target
Human Basic Cytokeratin
Host
Mouse
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Clone
BCCK1-1
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Ready-to-Use. Also available Unmodified or Azide-free.
Applications
  • IHC
  • IHC - Paraffin (1:1)
  • Immunofluorescence
  • Western blot
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Amino acid sequence common to basic keratins.
Specificity
Human Basic Cytokeratin
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. There are two types of cytokeratins/keratins/CKs: the acidic type I cytokeratins and the basic or neutral type II cytokeratins. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus this specific keratin fingerprint allows the classification of all epithelia upon their keratin expression profile. Furthermore this applies also to the malignant counterparts of the epithelia (carcinomas), as the keratin profile tends to remain constant when an epithelium undergoes malignant transformation. The main clinical implication is that the study of the keratin profile by immunohistochemistry techniques is a tool of immense value widely used for tumor diagnosis and characterization in surgical pathology. Titering of the Basic Cytokeratin antibody may be required for optimal performance. FFPE testing requires sections to be boiled in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. This Basic Cytokeratin antibody detects the following keratins/CKs: CK1 (67kDa), CK3 (64kDa), CK4 (59kDa), CK5 (58 kDa), CK6 (56kDa), CK8 (52 kDa).
Presentation
PBS, 0.01% BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Requested From: United States
Date Requested: 1/29/2020