Human BAFF / TNFSF13B

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

2B

Unconjugated

Protein A purified

Unmodified

Recombinant human CD257.

Recognizes CD257 (otherwise known as BAFF/BLyS), a 285 amino acid type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, which acts as a B and T cell stimulator and plays a role in the development of autoimmune diseases such as systemic lupus erythematosus. CD257 is expressed by monocytes, macrophages, T cells and dendritic cells and acts through binding to CD267 (TACI), CD269 (BCMA) and CD268 (BAFFR) receptors, the latter interaction playing a critical role in the activation, survival, differentiation and proliferation of B cells.

• ELISA (5 - 6 µg/ml)

PBS

Reconstitute with distilled water.

Before reconstitution store at 4°C. After reconstitution store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q9Y275 NCBI: NM_006573 NP_006564.1