BAD

BCL2-associated agonist of cell death

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain containing pro-apoptotic proteins, such as Bax, Bid, and Bik, form a growing subclass of the Bcl-2 family. Another such protein is the Bcl-2-antagonist of cell death (Bad). Bad regulates apoptosis by forming heterodimers with anti-apoptotic proteins Bcl-2 and Bcl-xL, thereby preventing them from binding with Bax. Bad activity is regulated by its phosphorylation; it is inactivated by kinases such as Akt and MAP kinase and thus promotes cell survival, whereas JNK-induced phosphorylation promotes the apoptotic role of Bad.

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Products

Antibodies (328)

ELISA Kits (21)

Proteins (12)

Type

Cell-Based (1)

Cell-Based Phosphorylation (5)

Custom (2)

Over-Expression Lysate (7)

Primary (328)

Recombinant (5)

Sandwich (12)

Sandwich CLIA (1)

Target

BAD (361)

Reactivity

Human (257)

Mouse (152)

Rat (96)

Bat (3)

Bovine (7)

Chicken (1)

Chimpanzee (6)

Dog (1)

Drosophila (1)

Gibbon (6)

Guinea pig (6)

Hamster (1)

Horse (3)

Monkey (13)

Pig (1)

Porcine (1)

Rabbit (20)

Sheep (1)

Xenopus (3)

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IHC (114)

IHC-Fr (3)

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WB (169)

Flo (3)

DB (154)

ELISA (209)

ICC (2)

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rabbit (319)

mouse (9)

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IHCPlus (1)

PathPlus Neuro (2)

Isotype

IgG (231)

IgG1 (8)

IgG2a,l (1)

Clonality

monoclonal mc (11)

polyclonal pc (317)

Clone

1G5B3 (1)

3H8 (1)

Format

12 x 8-Well Microstrips (1)

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96-Well Strip Plate (10)

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Azide-free (29)

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PerCP Conjugated (2)

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Unconjugated (142)

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Epitope

pSer134 (16)

pSer99 (14)

pSer112 (11)

pSer155 (10)

aa1-168 (8)

pSer118 (8)

pSer75 (8)

pSer91 (8)

aa53-81 (7)

aa92-127 (7)

pSer109 (7)

pSer111 (7)

pSer124 (7)

pSer161 (7)

pSer25 (7)

pSer32 (7)

pSer34 (7)

pSer57 (7)

pSer71 (7)

pSer74 (7)

pSer96 (7)

pSer97 (7)

pThr137 (7)

pThr80 (7)

pThr94 (7)

pTyr110 (7)

pTyr113 (7)

pTyr76 (7)

C-Terminus (6)

Ser118 (6)

pSer136 (6)

aa65-114 (4)

30-110 aa (2)

70-150 aa (2)

aa1-50 (2)

40-120 aa, Internal (1)

Ab-91/128 (1)

Arg149 (1)

Cleaved-Asp71 (1)

Phe130 (1)

Pro102 (1)

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aa100-149 (1)

aa102-151 (1)

aa119-168 (1)

aa2-23 (1)

aa21-70 (1)

aa61-110 (1)

aa87-103 (1)

p112 (1)

p134 (1)

p136 (1)

p155 (1)

pSer91/128 (1)

pSer91/Ser128 (1)

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Publications

No (361)

Sample Type

Adherent Cell Cultures (6)

Cell Lysates (1)

Plasma (8)

Serum (8)

Tissue Homogenates (4)

Tag

8His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (7)

Species

Human (9)

Source

293T Cells (3)

E. coli (2)

HEK 293 Cells (5)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

IHC-plus™ BAD Antibody LS-B12854

(4.0) Rating

Antibody:

BAD Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Drosophila, Pig, Rat, Hamster, Rabbit, Mouse, Dog, Sheep, Bovine, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$505

Select

BAD Antibody (phospho-Ser118) LS-C97416

Antibody:

BAD Rabbit anti-Human Polyclonal (pSer118) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

BAD Antibody (phospho-Ser136) LS-C74589

Antibody:

BAD Rabbit anti-Mouse Monoclonal (pSer136) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$665

Select

BAD Antibody (phospho-Ser136) LS-C801220

Antibody:

BAD Rabbit anti-Human Polyclonal (pSer136) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PathPlus™ BAD Antibody LS-B16581

Neuroscience

(5.0) Rating

Antibody:

BAD Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

BAD Antibody (phospho-Ser112) LS-C3894

Antibody:

BAD Rabbit anti-Mouse Polyclonal (pSer112) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µl/$688

Select

BAD Antibody (Pro102) LS-C74590

Antibody:

BAD Rabbit anti-Human Monoclonal (Pro102) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$469; 100 µl/$702

Select

PathPlus™ BAD Antibody (aa119-168) LS-B7566

Neuroscience

(5.0) Rating

Antibody:

BAD Rabbit anti-Human Polyclonal (aa119-168) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$440

Select

BAD Antibody LS-C441

Antibody:

BAD Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

Select

BAD Antibody (phospho-Ser134) LS-C822184

Antibody:

BAD Rabbit anti-Human Polyclonal (pSer134) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

BAD Antibody LS-C358658

Antibody:

BAD Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IP, WB

Format:

Unconjugated

Price:

50 µl/$393

Select

BAD Antibody (phospho-Ser155) LS-C801219

Antibody:

BAD Rabbit anti-Human Polyclonal (pSer155) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

BAD Antibody (phospho-Ser99) LS-C97419

Antibody:

BAD Rabbit anti-Human Polyclonal (pSer99) Antibody

Reactivity:

Human

Applications:

DB, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

BAD Antibody (phospho-Ser134) LS-C198668

Antibody:

BAD Rabbit anti-Human Polyclonal (pSer134) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

BAD Antibody (30-110 aa) LS-C381353

Antibody:

BAD Rabbit anti-Human Polyclonal (30-110 aa) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

BAD Antibody (70-150 aa) LS-C381541

Antibody:

BAD Rabbit anti-Human Polyclonal (70-150 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

BAD Antibody (70-150 aa) LS-C382269

Antibody:

BAD Rabbit anti-Human Polyclonal (70-150 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

BAD Antibody LS-C801662

Antibody:

BAD Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

BAD Antibody LS-C813340

Antibody:

BAD Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

BAD Antibody (aa92-127) LS-C98866

Antibody:

BAD Rabbit anti-Human Polyclonal (aa92-127) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

BAD Antibody LS-C331583

Antibody:

BAD Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

BAD Antibody (Pro130) LS-C176582

Antibody:

BAD Rabbit anti-Human Polyclonal (Pro130) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

BAD Antibody LS-C148207

Antibody:

BAD Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$386

Select

BAD Antibody (aa2-23) LS-C148206

Antibody:

BAD Rabbit anti-Mouse Polyclonal (aa2-23) Antibody

Reactivity:

Mouse, Rat

Applications:

IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$386

Select

BAD Antibody (phospho-Ser99) LS-C326915

Antibody:

BAD Rabbit anti-Human Polyclonal (pSer99) Antibody

Reactivity:

Human

Applications:

DB, ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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