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BACE1 / BACE Antibody LS‑C74520

Catalog Number Size Price
LS-C74520-100 100 µg $740 
Antibody

BACE1 / BACE Antibody LS‑C74520

Antibody:
Mouse Monoclonal to Human BACE1 / BACE
Application:
WB, IP, ELISA, Neut
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$740 
LS-C74520-100
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human BACE1 / BACE
Application:
WB, IP, ELISA, Neut
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
BACE antibody LS-C74520 is an unconjugated mouse monoclonal antibody to BACE (BACE1 ) from human and mouse. Validated for ELISA, IP, Neut and WB.
Target
Human BACE1 / BACE
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
  • ELISA
  • Neutralization
Immunogen
NS0-derived rhBACE-1 ectodomain.
Specificity
Recognizes human BACE-1 ectodomain. Species cross-reactivity: Mouse.
Usage
Suitable for use in ELISA, Immunoprecipitation/ Western Blot and Neutralization. The enzyme was then assayed with a peptide substrate. 50% of the proteolytic activity was inhibited by the antibody at 10 ug/ml (IC50) under conditions in which the enzyme was present at 10 ug/ml and the substrate concentration was 10uM. Considering the molecular masses of the enzyme (75kD) and the antibody (150kD), IC50 was achieved at ~0.5:1 molar ratio of the antibody to the enzyme. Did not inhibit rhCathepsin D activity under the same conditions.
Presentation
Lyophilized PBS, pH 7.4, 5% Trehalose
Reconstitution
Reconstitute in sterile PBS.
Storage
Lyophilized and resuspended forms: store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About BACE1 / BACE
P56817 NM_012104 NP_036236.1

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Requested From: United States
Date Requested: 9/16/2019