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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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B1R / BDKRB1 Antibody (Cytoplasmic Domain) IHC‑plus™ LS‑A799 Best Seller
BDKRB1 antibody LS-A799 is an unconjugated rabbit polyclonal antibody to human BDKRB1 (B1R). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Catalog
Size
Price
LS-A799-50
50 µg (1 mg/ml)
$425
In Stock for Immediate Shipment

Popular B1R / BDKRB1 Products

Anti-BDKRB1 antibody LS-A3579 IHC of human smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Applications: IHC, IHC - Paraffin
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Monkey
Applications: IHC, IHC - Paraffin
BDKRB1 monoclonal antibody (M04), clone 3A2. Western Blot analysis of BDKRB1 expression in MCF-7.
Species: Human
Applications: Western blot, ELISA
Western blot of BDKRB1 Antibody in HepG2 cell line lysates (35 ug/lane). BDKRB1 (arrow) was detected using the purified antibody.
Species: Human
Applications: Western blot, Flow Cytometry

Product Description

BDKRB1 antibody LS-A799 is an unconjugated rabbit polyclonal antibody to human BDKRB1 (B1R). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.

Specifications

Target
Human B1R / BDKRB1
Synonyms
BDKRB1, BKB1R, Bradykinin receptor 1, B1BKR, B1R, Bk b1 receptor, BK-1 receptor, BRADYB1, Bradykinin receptor B1, Kinin b1 receptor, B1 bradykinin receptor, BKR1, Bradykinin B1 receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • ELISA
Immunogen
B1R / BDKRB1 antibody was raised against synthetic 16 amino acid peptide from 1st cytoplasmic domain of human BDKRB1. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (94%); Horse (81%).
Blocking Peptide
LS-E29303 - Liquid - 50 µg 1 mg/ml - $145.00
Immunizing peptide used to generate LS-A799. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Cytoplasmic Domain
Specificity
Human BDKRB1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About B1R / BDKRB1
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. P46663 NM_000710 NP_000701.2


Publications (2)

1
Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin B1 receptor agonist in a glioma rat model. Ct J, Bovenzi V, Savard M, Dubuc C, Fortier A, Neugebauer W, Tremblay L, Mller-Esterl W, Tsanaclis AM, Lepage M, Fortin D, Gobeil F. PloS one. 2012 7:e37485. (WB; Human) [Full Text Article] [PubMed:22629405] [PMC:PMC3357387]
2
Structure-activity relationships of novel peptide agonists of the human bradykinin B2 receptor. B[Character e9]langer S, Bovenzi V, C[Character f4]t[Character e9] J, Neugebauer W, Amblard M, Martinez J, Lammek B, Savard M, Gobeil F. Peptides. 2009 Apr;30:777-87. [Full Text Article] [PubMed:19111586]

Customer Reviews (0)


Images

Immunohistochemistry

Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.

Immunohistochemistry

Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.

Immunohistochemistry

Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.

Immunohistochemistry

Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.

Immunohistochemistry

Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.

Immunohistochemistry

Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.

Immunohistochemistry

Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.

Immunohistochemistry

Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.
Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A799 dilution 5 ug/ml.

Requested From: United States
Date Requested: 10/19/2018

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