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Catalog Number Size Price
LS-C45373-1 1 ml $616 
Antibody

Monoclonal Mouse anti‑Human B cell Antibody (clone FMC7, FITC) LS‑C45373

Monoclonal Mouse anti‑Human B cell Antibody (clone FMC7, FITC) LS‑C45373

Antibody:
B cell Mouse anti-Human Monoclonal (FITC) (FMC7) Antibody
Application:
Flo
Reactivity:
Human
Format:
FITC, Unmodified
Price
Catalog Number
$616
LS-C45373-1
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
B cell Mouse anti-Human Monoclonal (FITC) (FMC7) Antibody
Application:
Flo
Reactivity:
Human
Format:
FITC, Unmodified

Specifications

Description
B cell antibody LS-C45373 is an FITC-conjugated mouse monoclonal antibody to human B cell. Validated for Flow.
Target
Human B cell
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgM Monoclonal
Clone
FMC7
Conjugations
FITC
Purification
Gel filtration
Modifications
Unmodified
Immunogen
HRIK cells - Human B-Lymphoblastoid line.
Specificity
Recognizes a glycoprotein antigen of 105kD expressed by B lymphocytes. The FMC7 antigen is expressed by peripheral B lymphocytes, and has been used widely in the study of B cell malignancy. FMC7 has been used extensively to differentiate various types of B cell malignancy. B-CLL is generally considered to be negative for FMC7 expression, but strong staining is seen in many other types of B cell lymphoma, including prolymphocytic leukemia and hairy cell leukemia. The nature of the FMC7 antigen has remained poorly defined following its first description in 1981. The expression pattern closely corresponds to that seen with CD22, but studies have shown that FMC7 does not recognize the CD22 molecule itself. A recent publication by Serke et al has shown Recognizes a conformational epitope on the CD20 molecule, most likely a multimeric complex of CD20.
Applications
  • Flow Cytometry (1:1)
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
TRIS Buffered Glycine, 0.1% Sodium Azide, 0.2% BSA
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/13/2022