Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey, Mouse, Hamster
(tested or 100% immunogen sequence identity)
IHC - Paraffin
Western blot (1:250 - 1:500)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
ATM antibody was raised against recombinant human ATM fragment (aa1980-2338).
Recognizes the human ATM protein, a 350kD polypeptide that is the product of the ATM gene. Species cross-reactivity: Monkey, mouse and hamster.
Suitable for use in Western Blot and Immunohistochemistry (paraffin). Western Blot: 1:250-1:500. Immunohistochemistry (Paraffin): 1:25. Paraffin sections require antigen retrieval using heat treatment prior to staining. Two hour incubation with the antibody is recommended.
PBS, 0.1% Sodium Azide, 40% Glycerol
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism.