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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ATF2 Antibody (phospho‑Ser490/Ser498) LS‑C245
Note: This antibody replaces LS-C54354, LS-C49263
ATF2 antibody LS-C245 is an unconjugated rabbit polyclonal antibody to ATF2 from human and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C245-100
100 µl
Unavailable

Popular ATF2 Products

Staining (0.5?g/ml) of Human Placenta lysate (RIPA buffer, 35?g total protein per lane). Detected by chemiluminescence.
Species: Human, Monkey, Bovine, Pig, Rabbit
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
ATF2 antibody LS-C31200 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, Western blot
Anti-ATF2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1170 concentration 10 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Anti-ATF2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6524 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
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Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

ATF2 antibody LS-C245 is an unconjugated rabbit polyclonal antibody to ATF2 from human and rat. Validated for IHC and WB.
About ATF2
Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'). P15336 NM_001880 NP_001871.2

ATF2 Antibody, CREB-2 Antibody, CRE-BP1 Antibody, CREB2 Antibody, HB16 Antibody, TREB7 Antibody, CREBP1 Antibody


Specifications

Target
Human ATF2
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:1000)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ATF2 antibody was raised against synthetic phosphopeptide corresponding to amino acid residues surrounding the phosphoSer490498 of human ATF2.
Epitope
pSer490/Ser498
Specificity
Specific for ~74k ATF2 protein phosphorylated at Ser490498. The antibody also recognizes the phosphorylated ~54k splice form of ATF2.
Presentation
50 uL of 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50% glycerol.
Storage
Short term: -20°C; Long term: -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.
Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.

Western blot

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immuno-labeling of the ~54k splice form of the phospho-ATF2 protein and the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.
Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immuno-labeling of the ~54k splice form of the phospho-ATF2 protein and the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.

Western blot

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.
Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.

Western blot

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immuno-labeling of the ~54k splice form of the phospho-ATF2 protein and the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.
Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immuno-labeling of the ~54k splice form of the phospho-ATF2 protein and the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.

Western blot

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.
Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.

Western blot

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immuno-labeling of the ~54k splice form of the phospho-ATF2 protein and the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.
Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immuno-labeling of the ~54k splice form of the phospho-ATF2 protein and the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.

Western blot

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.
Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.

Western blot

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immuno-labeling of the ~54k splice form of the phospho-ATF2 protein and the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.
Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immuno-labeling of the ~54k splice form of the phospho-ATF2 protein and the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.


Requested From: 
Date Requested: 6/21/2018

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