Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

AREG / Amphiregulin

amphiregulin

AREG / Amphiregulin is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.

Gene Name: amphiregulin
Synonyms: AREG, Amphiregulin, CRDGF, SDGF
Target Sequences: NM_001657 NP_001648.1 P15514

Publications (2)

1
Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis. Maximilian Strunz , Lukas M Simon , Meshal Ansari, Jaymin J Kathiriya, Ilias Angelidis, Christoph H Mayr, George Tsidiridis, Marius Lange, Laura F Mattner, Min Yee, Paulina Ogar, Arunima Sengupta, Igor Kukhtevich, Robert Schneider, Zhongming Zhao, Carola Voss, Tobias Stoeger, Jens H L Neumann, Anne Hilgendorff, Jürgen Behr, Michael O'Reilly, Mareike Lehmann, Gerald Burgstaller, Melanie Königshoff, Harold A Chapman, Fabian J Theis, Herbert B Schiller. Nature communications. 2020 July;11:3559. [Full Text Article] [PubMed:32678092] [PMC:PMC7366678] Related Antibodies: LS-B13911.
2
DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation. Hung-Hsi Chen, Hsin-I Yu, Rudy Rudy, Sim-Lin Lim, Yi-Fen Chen, Shu-Hsing Wu, Shu-Chun Lin, Muh-Hwa Yang, Woan-Yuh Tarn. iScience. 2021 Sep;24:103086. [Full Text Article] [PubMed:34568799] [PMC:PMC8449240]

☰ Filters
Antibodies (76)
ELISA Kits (40)
Proteins (16)
Competitive EIA (2)
Custom (1)
Development Kit (1)
Over-Expression Lysate (2)
Primary (76)
Recombinant (14)
Sandwich (29)
Sandwich CLIA (7)
AREG / Amphiregulin (132)
Human (68)
Mouse (25)
Rat (31)
Bovine (10)
Chicken (1)
Cow (8)
Guinea pig (1)
Monkey (1)
Pig (2)
Rabbit (1)
Sheep (1)
IHC (6)
IHC-P (2)
WB (72)
Flo (1)
ELISA (11)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (50)
mouse (26)
Product Group
DevKit DuoPlus (1)
IHCPlus (1)
IgG (28)
IgG2b,k (17)
monoclonal mc (25)
polyclonal pc (51)
3E4 (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (10)
96-Well Strip Plate (26)
Antibody Pair and Standard (1)
APC (6)
APC Conjugated (7)
Biotin Conjugated (10)
Cy3 Conjugated (6)
Cy7 Conjugated (6)
FITC Conjugated (9)
HRP Conjugated (9)
PE Conjugated (7)
Unconjugated (22)
aa20-100 (16)
aa27-247 (8)
aa97-243 (8)
aa91-140 (4)
91-140 aa, Internal (1)
No (130)
Yes (2)
Breast Milk (1)
Cell Culture Supernatants (11)
Cell Lysates (5)
Plasma (37)
Saliva (1)
Serum (37)
Tissue Homogenates (9)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His-GST (2)
His-T7 (1)
Myc-DDK (Flag) (2)
Bovine (1)
Human (12)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (11)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (6)
Biologically active (4)
AREG / Amphiregulin Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
AREG / Amphiregulin Rabbit anti-Human Polyclonal (aa20-100) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
Select
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
15~20 kDa (SDS-PAGE)
50 µg/$296; 10 µg/$253
AREG / Amphiregulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
AREG / Amphiregulin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
16.46 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
AREG / Amphiregulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
AREG / Amphiregulin ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
1.37 - 1000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$1,034
Select
AREG / Amphiregulin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
AREG / Amphiregulin ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
AREG / Amphiregulin ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
1.37 - 1000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$968
AREG / Amphiregulin Protein - BALB/3T3 cell proliferation induced by mouse amphiregulin.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 98 amino acid recombinant protein has a predicted molecular mass of approximately 11.3 kD. The DTT-reduced and non-reduced protein migrate at approximately 16 kD and by SDS-PAGE. The N-terminal amino acid is Ser.
10 µg/$268; 25 µg/$318
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
11.3 kDa
10 µg/$268; 50 µg/$349
AREG / Amphiregulin Antibody - 1:100 staining rat heart tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
AREG / Amphiregulin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
AREG / Amphiregulin Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
AREG / Amphiregulin Antibody - Western blot analysis of extracts of various cell lines, using AREG antibody.
Select
AREG / Amphiregulin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
AREG / Amphiregulin Antibody - AREG monoclonal antibody (M06), clone 3E4. Western Blot analysis of AREG expression in human pancreas.
Select
AREG / Amphiregulin Mouse anti-Human Monoclonal (3E4) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
AREG / Amphiregulin Antibody - Western Blot; Sample: Recombinant AREG, Human.
Select
AREG / Amphiregulin Mouse anti-Human Monoclonal Antibody
Rat, Human
WB
Unconjugated
100 µl/$295; 200 µl/$331; 500 µl/$451; 1 ml/$511; 2 ml/$648; 5 ml/$1,099
AREG / Amphiregulin Antibody - AREG / Amphiregulin antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
AREG / Amphiregulin Rabbit anti-Human Polyclonal (aa91-140) Antibody
Human
WB
Unconjugated
100 µl/$424
AREG / Amphiregulin Antibody - Immunohistochemistry of paraffin-embedded human breast cancer tissue using AREG Antibody at dilution of 1:100
Select
AREG / Amphiregulin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
AREG / Amphiregulin ELISA Kit
Select
Sandwich
96-Well Microplate
Rabbit
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
AREG / Amphiregulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
AREG / Amphiregulin Protein - 12.5% SDS-PAGE of human AREG stained with Coomassie Blue
Select
Wheat Germ Extract
GST
54.3 kDa
10 µg/$479; 25 µg/$670
AREG / Amphiregulin Antibody - Western blot analysis of Amphiregulin using anti-Amphiregulin antibody. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: rat brain tissue lysates,Lane 2: mouse brain tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Amphiregulin antigen affinity purified polyclonal antibody at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1% Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit with Tanon 5200 system. A specific band was detected for Amphiregulin at approximately 41KD. The expected band size for Amphiregulin is at 28KD.
Select
AREG / Amphiregulin Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
AREG / Amphiregulin Antibody - Anti-Human Amphiregulin Western Blot Unreduced
Select
AREG / Amphiregulin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
AREG / Amphiregulin Antibody - Western blot testing of 1) rat brain and 2) mouse brain lysate with Amphiregulin antibody at 0.5ug/ml. Molecular weight: 28 kDa (non-glycosylated), ~50 kDa (glycosylated pro form), ~43 kDa (predominant glycosylated soluble form) as well as other, smaller, soluble and membrane bound forms.
Select
AREG / Amphiregulin Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µg/$575
AREG / Amphiregulin Antibody - Western blot of Amphiregulin antibody
Select
AREG / Amphiregulin Rabbit anti-Human Polyclonal (91-140 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Viewing 1-25 of 132 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).