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Catalog Number Size Price
LS-C390460-20 20 µg (0.2 mg/ml) $340 
LS-C390460-100 100 µg (0.2 mg/ml) $501 
AR / Androgen Receptor Antibody - Formalin-fixed, paraffin-embedded human prostate carcinoma stained with Androgen Receptor antibody (AR441 + DHTR/882).  This image was taken for the unmodified form of this product. Other forms have not been tested.

Monoclonal Mouse anti‑Human AR / Androgen Receptor Antibody (clone AR441 + DHTR/882, aa300‑316, IHC, IF) LS‑C390460

Monoclonal Mouse anti‑Human AR / Androgen Receptor Antibody (clone AR441 + DHTR/882, aa300‑316, IHC, IF) LS‑C390460

Note: This antibody replaces LS-C20618
Antibody:
AR / Androgen Receptor Mouse anti-Human Monoclonal (aa300-316) (AR441 + DHTR/882) Antibody
Application:
IHC, IHC-P, IF
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$340
LS-C390460-20
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
AR / Androgen Receptor Mouse anti-Human Monoclonal (aa300-316) (AR441 + DHTR/882) Antibody
Application:
IHC, IHC-P, IF
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Androgen Receptor antibody LS-C390460 is an unconjugated mouse monoclonal antibody to human Androgen Receptor (AR) (aa300-316). Validated for IF and IHC.
Target
Human AR / Androgen Receptor
Synonyms
AR | Androgen receptor | Dihydrotestosterone receptor | DHTR | AIS | KD | NR3C4 | HUMARA | SBMA | TFM | SMAX1 | HYSP1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse
Clonality
IgG Monoclonal
Clone
AR441 + DHTR/882
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Ready-to-Use, Azide-free, BSA-free.
Immunogen
Synthetic peptide (STEDTAEYSPFKGGYTK, aa300-316 of UniProt P10275) of human AR (AR441) and recombinant human AR protein (DHTR/882). Percent identity by BLAST analysis: Human (100%); Mouse, Sheep, Bovine, Pig (82%).
Epitope
aa300-316
Specificity
Human AR / Androgen receptor
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Immunofluorescence (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This mAb is superb for staining of formalin/paraffin tissues. Optimal dilution of the Androgen Receptor antibody cocktail should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About AR / Androgen Receptor
P10275 NM_000044 NP_000035.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/12/2021