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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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AQP4 / Aquaporin 4 Antibody (aa280‑296) LS‑C3805
Aquaporin 4 antibody LS-C3805 is an unconjugated rabbit polyclonal antibody to rat Aquaporin 4 (AQP4). Validated for ELISA, IHC and WB. Cited in 1 publication.
Antibody
Catalog
Size
Price
LS-C3805-100
100 µg (1 mg/ml)
$755

Popular AQP4 / Aquaporin 4 Products

AQP4 / Aquaporin 4 antibody. IHC(P): Rat Brain Tissue.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: Western blot
IF analysis of Aquaporin 4 in rat kidney tissue using a 1:200 dilution of AQP4 / Aquaporin 4 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
Applications: Immunofluorescence, Western blot
Western blot of recombinant AQP4 / Aquaporin 4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse
Applications: IHC, Western blot

Product Description

Aquaporin 4 antibody LS-C3805 is an unconjugated rabbit polyclonal antibody to rat Aquaporin 4 (AQP4). Validated for ELISA, IHC and WB. Cited in 1 publication.

Specifications

Target
Rat AQP4 / Aquaporin 4
Synonyms
AQP4, Aquaporin type4, Aquaporin 4, Aquaporin-4, HMIWC2, MIWC, WCH4, AQP-4
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (2 - 10 µg/ml)
  • Western blot (1 - 10 µg/ml)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide 17aa sequence corresponding to aa280-296 in the region near the carboxy terminus of the rat AQP4 (1,2) (KLH coupled via cysteine amino terminal). This peptide is predicted to be cytoplasmic (2).
Epitope
aa280-296
Specificity
Recognizes rat Aquaporin 4 (AQ, WCH4; MIWC). Immunizing sequence is unique to AQP4. Species sequence Homology: mouse: 94%; bovine: 88%, rabbit: 86%, human: 82%.
Usage
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Presentation
PBS, pH 7.5, 0.1% BSA, 40% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About AQP4 / Aquaporin 4
AQP4, also known as Mercurial-insensitive water channel (MIWC), is the fourth member of the aquaporin water channel family. This osmoreceptor regulates body water balance and mediates water flow within the central nervous system. It appears to play some specific role in the functioning of skeletal muscles, retina, and auditory system. Contrary to other aquaporin family members, AQP4 is not inhibited by mercurial compounds. P55087 NM_001650 NP_001641.1


Publications (1)

1
Aquaporin pathways and mucin secretion of Bowman's glands might protect the olfactory mucosa. Solbu TT, Holen T. Chemical senses. 2012 37:35-46. (IHC; Rat) [Full Text Article] [PubMed:21745799]

Customer Reviews (0)


Requested From: United States
Date Requested: 10/17/2018

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