Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Western blot (1 - 10 µg/ml)
ELISA (0.5 - 1 µg/ml)
A 19aa synthetic peptide sequence corresponding to the N-terminal, extracellular domain of mouse AQP2.
Recognizes mouse AQP2 at ~30kD. Species sequence Homology: Rat-100%, sheep-78%, human -73%.
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml using Chemiluminescence. ELISA: 0.5-1 ug/ml. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, pH 7.2, No preservatives added, No stabilizing proteins added
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.