Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
AQP1, Aquaporin-1, AQP-1, AQP-CHIP, Aquaporin 1, Aquaporin-CHIP, CHIP28, Colton blood group, Urine water channel, CO
(tested or 100% immunogen sequence identity)
Human, Mouse, Bovine (at least 90% immunogen sequence identity)
Western blot (1:1000 - 1:5000)
Synthetic peptide 19aa sequence corresponding to the C-terminal, cytoplasmic domain of rat AQP1 (KLH). No significant sequence homology to any other known eukaryotic protein. Species Sequence Homology: Mouse, human and bovine - 100%.
Recognizes rat Aquaporin 1 (AQP1, CHIP-28) at 28kD. No significant sequence homology to any other known eukaryotic protein. Species sequence Homology: Mouse, human and bovine, 100%.
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000. Using ECL.
PBS, 0.05% Sodium Azide, 40% Glycerol
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Aquaporin-1 (AQP1), also known as Channel-forming integral membrane protein (CHIP), is the first member of the aquaporin water channel family. It plays a role in the transmembrane water transport, especially in kidneys, red blood cells, central nervous system and some epithelial surfaces. Its activity can be blocked by mercurial compounds. AQP1 is associated with so-called Colton blood group antigens.