LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
APAF1 / APAF‑1 Antibody (aa1‑97) LS‑C3749
APAF-1 antibody LS-C3749 is an unconjugated rat monoclonal antibody to APAF-1 (APAF1) from mouse and rat. Validated for ICC, IP and WB.
Antibody
Catalog
Size
Price
LS-C3749-100
100 µg
$665

Popular APAF1 / APAF-1 Products

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation, ELISA
Immunohistochemistry of Apaf1 in human skin tissue with Apaf1 antibody at 20 µg/ml.
Species: Human, Mouse, Rat
Applications: IHC, Western blot
Formalin-fixed, paraffin-embedded tissue sections of human brain tumors stained for Apaf 1 expression using LS-C148201 at 1:2000. A. Gemistocytoma (grade II). B. Anaplastic glioma. A high level of Apaf 1was observed in the gemistocytoma whereas a low level was seen in the more malignant anaplastic glioma. Hematoxylin-Eos in counterstain.
Species: Human, Mouse, Rat, Gerbil
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Immunofluorescence of Apaf1 in K562 cells with Apaf1 antibody at 10 ug/ml.
Species: Human, Mouse, Rat
Applications: Immunofluorescence, Western blot
Anti-APAF1 / APAF-1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3340 concentration 10 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin

Product Description

APAF-1 antibody LS-C3749 is an unconjugated rat monoclonal antibody to APAF-1 (APAF1) from mouse and rat. Validated for ICC, IP and WB.

Specifications

Target
Mouse APAF1 / APAF-1
Synonyms
APAF1, APAF-1, CED4, KIAA0413
Host
Rat
Reactivity
Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ICC
  • Western blot
  • Immunoprecipitation
Immunogen
APAF1 / APAF-1 antibody was raised against recombinant mouse Apaf-1 (apoptosis protease-activating factor 1) (aa 1-97) containing the N-terminal CARD domain.
Epitope
aa1-97
Specificity
Recognizes the CARD domain of mouse and rat Apaf-1. Does not cross-react with human Apaf-1.
Usage
Immunocytochemistry. Immunoprecipitation. Western Blot.
Presentation
PBS, 0.02% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About APAF1 / APAF-1
Apaf1 has been described as the core of the apoptosome. Deficiency in murine Apaf1 leads to embryonic lethality with a phenotype affecting many aspects of developmental apoptosis. In the developing brain, Apaf1 is a death regulator of the neuronal founder cells. Combined intercrosses of mouse lines mutant for members of the mitochondrial death pathway are providing us with some clues about the relative regulation existing among neuronal cell populations. O14727 NM_013229 NP_037361.1


Publications (0)


Customer Reviews (0)


Requested From: United States
Date Requested: 10/18/2018

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy