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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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AOC3 / VAP‑1 Antibody (aa712‑724) IHC‑plus™ LS‑B2763 Best Seller
Note: This antibody replaces LS-C54512
VAP-1 antibody LS-B2763 is an unconjugated goat polyclonal antibody to VAP-1 (AOC3) from human and hamster. Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B2763-50
50 µg (0.5 mg/ml)
$425

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Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

AOC3 / VAP-1 Antibody (aa712-724) for IHC IHC-plus™ LS-B2763

Specifications

Target
Human AOC3 / VAP-1
Synonyms
AOC3, Copper amine oxidase, HPAO, Membrane primary amine oxidase, SSAO, VAP-1, VAP1, Vascular adhesion protein 1
Host
Goat
Reactivity
Human, Hamster (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Rat, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (3.75 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:64000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
AOC3 / VAP-1 antibody was raised against synthetic peptide C-DEDPSFYSADSIY from an internal region (near the C-terminus) of human AOC3 / VAP-1 (NP_003725.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Marmoset, Hamster (100%); Gibbon, Monkey, Mouse, Rat, Rabbit (92%); Elephant, Bovine (85%).
Blocking Peptide
LS-E26243 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B2763. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa712-724
Specificity
Human AOC3 / VAP-1.
Usage
Immunohistochemistry: LS-B2763 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2763 was determined to be 3.75 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About AOC3 / VAP-1
AOC3 / VAP-1 is a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. Q16853 NM_003734 NP_003725.1


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Immunohistochemistry

Anti-AOC3 / VAP-1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2763 concentration 75 ug/ml.
Anti-AOC3 / VAP-1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2763 concentration 75 ug/ml.

Immunohistochemistry

Anti-AOC3 / VAP-1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2763 concentration 75 ug/ml.
Anti-AOC3 / VAP-1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2763 concentration 75 ug/ml.

Immunohistochemistry

Anti-AOC3 / VAP-1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2763 concentration 75 ug/ml.
Anti-AOC3 / VAP-1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2763 concentration 75 ug/ml.

Immunohistochemistry

Anti-AOC3 / VAP-1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2763 concentration 75 ug/ml.
Anti-AOC3 / VAP-1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2763 concentration 75 ug/ml.

Requested From: United States
Date Requested: 10/16/2018

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