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E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes.
Gene Name: | Zinc finger, SWIM-type containing 2 |
Synonyms: | ZSWIM2, MEKK1-related protein X, MEX, ZZZ2 |
Target Sequences: | Q8NEG5 Q8NEG5 |
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