ZNRF1

zinc and ring finger 1, E3 ubiquitin protein ligase

E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes neurodegeneration by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons (Probable).

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Products

Antibodies (15)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (15)

Recombinant (2)

Target

ZNRF1 (19)

Reactivity

Human (14)

Mouse (6)

Rat (4)

Bat (3)

Bovine (4)

Chimpanzee (3)

Dog (1)

Guinea pig (4)

Hamster (4)

Monkey (3)

Pig (3)

Rabbit (3)

Zebrafish (3)

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Application

IHC (3)

IHC-P (2)

WB (15)

ELISA (8)

IF (1)

Peptide-ELISA (2)

Host

rabbit (13)

mouse (1)

goat (1)

Isotype

IgG (7)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (14)

Clone

1H4 (1)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (7)

Epitope

aa59-86 (7)

N-Terminus (4)

aa93-106 (1)

Publications

No (19)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

ZNRF1 Antibody LS-C809970

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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ZNRF1 Antibody (aa93-106) LS-C186637

Antibody:

ZNRF1 Goat anti-Mouse Polyclonal (aa93-106) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Hamster

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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ZNRF1 Antibody (clone 1H4) LS-C134112

Antibody:

ZNRF1 Mouse anti-Human Monoclonal (1H4) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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ZNRF1 Antibody (aa59-86) LS-C326737

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (aa59-86) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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ZNRF1 Antibody (aa59-86, Biotin) LS-C243561

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (aa59-86) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

ZNRF1 Antibody (aa59-86, FITC) LS-C243562

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (aa59-86) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

ZNRF1 Antibody (aa59-86, Azide-free, HRP) LS-C247415

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (aa59-86) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

ZNRF1 Antibody (aa59-86, APC) LS-C243559

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (aa59-86) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

ZNRF1 Antibody (aa59-86, PE) LS-C243564

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (aa59-86) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

ZNRF1 Antibody LS-C778548

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

ZNRF1 Antibody (N-Terminus) LS-C110427

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

ZNRF1 Antibody (N-Terminus, HRP) LS-C439044

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Zebrafish, Rat, Hamster, Rabbit, Mouse, Guinea pig, Bovine, Pig, Bat, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ZNRF1 Antibody (N-Terminus, Biotin) LS-C439042

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Zebrafish, Rat, Hamster, Rabbit, Mouse, Guinea pig, Bovine, Pig, Bat, Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

ZNRF1 Antibody (N-Terminus, FITC) LS-C439043

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Zebrafish, Rat, Hamster, Rabbit, Mouse, Guinea pig, Bovine, Pig, Bat, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ZNRF1 Antibody (aa59-86) LS-C160966

Antibody:

ZNRF1 Rabbit anti-Human Polyclonal (aa59-86) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

ZNRF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108948

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.8 kDa

Price:

100 µg/$494

Select

Human ZNRF1 Protein (Recombinant GST) (Full Length) - LS-G35868

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.2 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human ZNRF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92141

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.8 kDa

Price:

20 µg/$150

Select

Human ZNRF1 Protein (Recombinant GST, N-terminus) (aa74-178) - LS-G63419

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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