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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ZAP70 Antibody (clone GF1) LS‑C190316
Antibody
ZAP70 antibody LS-C190316 is an unconjugated mouse monoclonal antibody to human ZAP70. Validated for ELISA and IHC.
Catalog
Size
Price
LS-C190316-100
100 µl
Unavailable

Popular ZAP70 Products

IHC of paraffin-embedded human lymph showing cytoplasmic localization using ZAP70 antibody with DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Formalin-Fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and AEC chromogen. Note staining of T-Cells.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
IHC of paraffin-embedded human breast carcinoma, using ZAP-70 (Phospho-Tyr493) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-ZAP70 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7841 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Western blot of recombinant ZAP70.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Western blot

Product Description

ZAP70 antibody LS-C190316 is an unconjugated mouse monoclonal antibody to human ZAP70. Validated for ELISA and IHC.
About ZAP70
Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, as well as thymocyte development. Contributes also to the development and activation of primary B-lymphocytes. When antigen presenting cells (APC) activate T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 to the doubly phosphorylated TCR component CD247/CD3Z through ITAM motif at the plasma membrane. P43403 NM_207519 P43403

ZAP70 Antibody, 70 kDa zeta-associated protein Antibody, SRK Antibody, STCD Antibody, STD Antibody, Syk-related tyrosine kinase Antibody, Tyrosine-protein kinase ZAP-70 Antibody, TZK Antibody, ZAP-70 Antibody, Zeta-associated protein 70 Antibody


Specifications

Target
Human ZAP70
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [GF1]
Conjugations
Unconjugated
Purification
Ascites
Modifications
Unmodified
Applications
  • IHC (1:200 - 1:1000)
  • ELISA (1:10000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ZAP70 antibody was raised against purified recombinant fragment of human ZAP70 expressed in E. coli.
Specificity
Human
Presentation
Ascites, 0.03% sodium azide
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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