Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2C4] (IgG1,k) to Human YY1
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [2C4]
Protein A purified
IHC - Paraffin (5 µg/ml)
Immunofluorescence (10 µg/ml)
Specificity and Use
YY1 antibody was raised against yY1 (NP_003394, 221 a.a. ~ 321 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot using transfected cell lysates, cell line lysates and the recombinant protein used as the immunogen.
YY1 Antibody, Delta transcription factor Antibody, INO80S Antibody, NF-E1 Antibody, INO80 complex subunit S Antibody, YY1 transcription factor Antibody, YIN-YANG-1 Antibody, YY-1 Antibody, Yin and yang 1 Antibody, UCRBP Antibody, Yin and Yang 1 protein Antibody
Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Binds to the consensus sequence 5'-CCGCCATNTT-3'; some genes have been shown to contain a longer binding motif allowing enhanced binding; the initial CG dinucleotide can be methylated greatly reducing the binding affinity.