Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
YWHAZ / 14-3-3 Zeta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity.
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using. Rabbit Anti-14-3-3 zeta (Phospho-Ser58) Polyclonal Antibody.
Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and centrosomal staining using Rabbit Anti-14-3-3 zeta (Phospho-Ser58) Polyclonal Antibody.
Western blot of extract from NIH/3T3 cells, untreated or treated with TNF- alpha (20 ng/ml, 5 min) using. Rabbit Anti-14-3-3 zeta (Ab-58) Polyclonal Antibody (lane 1 and 2) and Rabbit Anti-14-3-3 zeta (Phospho-Ser58) Polyclonal Antibody (lane 3 and 4).