LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-YWHAB / 14-3-3 Beta Antibody (N-Terminus) LS-C42370

Ordering

Wt. Vol. Conc. Price
- 100 µl - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular YWHAB / 14-3-3 Beta Antibodies

Anti-YWHAB / 14-3-3 Beta Antibody (aa1-246, clone J2E9) IHC-plus™ LS-B2958
Mouse Monoclonal [clone J2E9] (IgG2a,k) to Human YWHAB / 14-3-3 Beta
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-YWHAB / 14-3-3 Beta Antibody IHC-plus™ LS-B4792
Rabbit Polyclonal to Human YWHAB / 14-3-3 Beta
Human, Zebrafish
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Sheep YWHAB / 14-3-3 Beta
Sheep, Human, Mouse, Rat, Bovine, Rabbit
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Sheep YWHAB / 14-3-3 Beta
Rabbit
Sheep, Human, Mouse, Rat, Bovine, Rabbit (tested or 100% immunogen sequence identity)
Fish, Yeast, Amphibia, Fungus, Invertebrates, Reptile
IgG Polyclonal
Unconjugated
Unmodified

Applications

  • IHC - Paraffin (1:600)
  • Western blot (1:3000)
  • ELISA

Specificity and Use

YWHAB / 14-3-3 Beta antibody was raised against synthetic peptide corresponding to acetylated N-terminal sequence of sheep 14-3-3 beta.
N-Terminus
Recognizes the acetylated N-terminal of 14-3-3 beta. It is a member of the 14-3-3 family which consists of 30 kD proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 beta plays a role in the pathogenesis of systemic lupus erythematosus and is involved in negative regulation of p90 ribosomal S6 kinase activity and tuberous sclerosis tumor suppressor proteins. It also binds IGF-1 receptor, RAF1 and CDC25 phosphatases. May not react with recombinant proteins that are not N-acetylated.
Western Blot: LS-C42370 detects a band of approximately 30kD in HEK293 cell lysates. Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.

Packaging

Serum, 0.09% sodium azide.
For research use only.

About YWHAB / 14-3-3 Beta

P31946 NM_003404 NP_003395.1

YWHAB Antibody, 14-3-3 alpha Antibody, 14-3-3 Beta Antibody, 14-3-3 protein beta/alpha Antibody, GW128 Antibody, Protein 1054 Antibody, HS1 Antibody, KCIP-1 Antibody, YWHAA Antibody

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.

Requested From: United States
Date Requested: 12/9/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number