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Yo / CDR2

cerebellar degeneration-related protein 2, 62kDa

Paraneoplastic cerebellar degeneration is a disorder of the cerebellum found in association with neoplasms of lung, ovary, breast, or Hodgkin's disease. Affected brains show extensive loss of Purkinje cells, variable loss of granule and basket neurons and proliferation of Bergman glia. These patients have a circulating antibody called anti-Yo. One of the proteins recognized by Yo is CDR2. CDR2 suppresses the transcriptional activity and DNA binding of nuclear factor-kappa B by and unknown mechanism.

Gene Name: cerebellar degeneration-related protein 2, 62kDa
Synonyms: CDR2, CDR62, Yo paraneoplastic antigen, PCD17, Yo
Target Sequences: M63256 AAA51961.1 Q01850

Publications (1)

1
CDR2L Is the Major Yo Antibody Target in Paraneoplastic Cerebellar Degeneration. Torbjørn Kråkenes, Ida Herdlevaer, Margrethe Raspotnig, Mette Haugen, Manja Schubert, Christian A Vedeler. Annals of neurology. 2019 August;86:316-321. [Full Text Article] [PubMed:31148214]

☰ Filters
Antibodies (33)
Proteins (8)
Over-Expression Lysate (2)
Primary (33)
Recombinant (6)
Yo / CDR2 (41)
Human (33)
Mouse (8)
Rat (4)
Bovine (5)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
Pig (3)
Primate (1)
Rabbit (3)
IHC (24)
IHC-P (10)
WB (32)
ELISA (19)
IF (4)
Peptide-ELISA (1)
rabbit (27)
mouse (6)
Product Group
IHCPlus (1)
IgG (19)
IgG2a,k (5)
IgG2b,k (1)
monoclonal mc (6)
polyclonal pc (27)
1F8 (1)
APC Conjugated (2)
Biotin Conjugated (5)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (13)
aa420-448 (7)
C-Terminus (6)
N-Terminus (4)
No (41)
6His, N-terminus (2)
GST (2)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (7)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (3)
Purified (3)
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E. coli
6His, N-terminus
55.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Yo / CDR2 Antibody - CDR2 antibody CDR2(cerebellar degeneration-related protein 2, 62kDa) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Yo / CDR2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
Yo / CDR2 Antibody - CDR2 antibody CDR2(cerebellar degeneration-related protein 2, 62kDa) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Yo / CDR2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
Yo / CDR2 Antibody - CDR2 antibody CDR2(cerebellar degeneration-related protein 2, 62kDa) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Yo / CDR2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
Yo / CDR2 Antibody - Brain, cerebellum.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Yo / CDR2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Bovine, Human, Primate
IHC, WB
Biotin Conjugated
0.1 ml/$416
Yo / CDR2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Yo / CDR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Yo / CDR2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Yo / CDR2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Yo / CDR2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Yo / CDR2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Yo / CDR2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
Yo / CDR2 Antibody - Immunoperoxidase of monoclonal antibody to CDR2 on formalin-fixed paraffin-embedded human adrenal gland. [antibody concentration 3 ug/ml]
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Yo / CDR2 Mouse anti-Human Monoclonal (1F8) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Bovine, Human, Monkey
ELISA, IHC, WB
Unconjugated
100 µl/$755
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (aa420-448) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (aa420-448) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (aa420-448) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (aa420-448) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (aa420-448) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (aa420-448) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
Yo / CDR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
Select
Yo / CDR2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
Select
Yo / CDR2 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, WB
FITC Conjugated
100 µl/$904
Select
Yo / CDR2 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, WB
PE Conjugated
100 µl/$904
Select
Yo / CDR2 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
Yo / CDR2 Antibody - CDR2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human cerebellum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (aa420-448) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
Yo / CDR2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, WB
Unconjugated
100 µl/$649
Yo / CDR2 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using CDR2 Polyclonal Antibody at dilution of 1:60.
Select
Yo / CDR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Viewing 1-25 of 41 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).