Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CDR2 Antibody, CDR62 Antibody, Yo paraneoplastic antigen Antibody, PCD17 Antibody, Yo Antibody
Paraneoplastic cerebellar degeneration is a disorder of the cerebellum found in association with neoplasms of lung, ovary, breast, or Hodgkin's disease. Affected brains show extensive loss of Purkinje cells, variable loss of granule and basket neurons and proliferation of Bergman glia. These patients have a circulating antibody called anti-Yo. One of the proteins recognized by Yo is CDR2.