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Anti-Yersinia pestis V Antigen Antibody (clone Va13) LS-C58384

Ordering

Wt. Vol. Conc. Price
200 µg - - $375
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Mouse Monoclonal [clone Va13] (IgG1) to Yersinia pestis V Antigen
Yersinia pestis
Western blot, ELISA
Unconjugated

Details

Yersinia pestis V Antigen
Mouse
Yersinia pestis (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [Va13]
Unconjugated
Affinity purified
Unmodified

Applications

  • Western blot
  • ELISA

Specificity and Use

Recognizes the V antigen of Yersinia pestis (also known as LcrV), a 327-residue soluble protein. Yersinia pestis is a Gram-negative bacillus belonging to the family Enterobacteriaceae. Infection in humans can take the form of bubonic, pneumonic and septicemic plague amongst other less common forms. All three forms have been known for very high mortality rates during several epidemics across the world, possibly including the Black Death that ravaged Europe from 1347-1353. Although such large epidemics have not been seen since the Great Plague of London in 1665-1666, the disease still exists and there is concern as to its use as a biological weapon. The V antigen has many complex functions. It mediates the delivery of toxins into host cell, can stimulate production of interleukin-10 (an immunosuppressive cytokine) and it can inhibit chemotaxis of polymorphonuclear neutrophils. Antibodies against LcrV protect against the plague. May be used as a capture antibody in ELISA assays for Y. pestis V antigen.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About Yersinia pestis V Antigen

P23994 P23994

pYV0057 Antibody, Y. pestis V Antigen Antibody

Involved in calcium regulation of yop expression, which includes the export process.

Requested From: United States
Date Requested: 12/3/2016

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