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Anti-XRCC5 / Ku80 Antibody (C-Terminus) LS-C31766

Catalog Size Price
LS-C31766-100 100 µg (1 mg/ml) Unavailable

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Anti-XRCC5 / Ku80 Antibody (clone 3241C1a) LS-C342487
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100% Guaranteed
Rabbit Polyclonal (IgG) to Human XRCC5 / Ku80
Human, Mouse, Bat, Horse, Pig
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human XRCC5 / Ku80
Rabbit
Human, Mouse, Bat, Horse, Pig (tested or 100% immunogen sequence identity)
Monkey, Rat, Bovine, Dog, Guinea pig, Rabbit (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Protein A purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot (1.25 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

XRCC5 / Ku80 antibody was raised against synthetic peptide from C-Terminus of human XRCC5 (Q4VBQ5, NP_066964). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset, Elephant, Bat, Horse, Opossum (100%); Monkey, Rat, Dog, Bovine, Rabbit, Guinea pig (92%); Hamster, Pig (85%); Galago, Mouse, Turkey, Chicken, Xenopus (84%).
LS-E12063 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C31766. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
C-Terminus
Human XRCC5 / Ku80

Packaging

Lyophilized from PBS with 2% sucrose
100 µl After adding water, will consist of PBS buffer with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About XRCC5 / Ku80

P13010 NM_021141 NP_066964.1

XRCC5 Antibody, 86 kDa subunit of Ku antigen Antibody, CTC85 Antibody, CTCBF Antibody, DNA repair protein XRCC5 Antibody, G22P2 Antibody, KARP-1 Antibody, Ku autoantigen, 80kDa Antibody, NFIV Antibody, KARP1 Antibody, Ku86 Antibody, KUB2 Antibody, TLAA Antibody, Nuclear factor IV Antibody, KU80 Antibody, Thyroid-lupus autoantigen Antibody

Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.

Immunohistochemistry

Immunohistochemistry
XRCC5 / Ku80 antibody LS-C31766 IHC of formalin-fixed, paraffin-embedded human Pancreas. Positive label: Epithelial cells of pancreatic acinus indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 12/13/2017

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