Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 3241C1a] (IgG1) to Human XRCC5 / Ku80
ICC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, Dot Blot
Rabbit Polyclonal (IgG) to Human XRCC5 / Ku80
IHC - Frozen, ICC, Western blot, ELISA
Human XRCC5 / Ku80
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
IHC - Frozen (1:200 - 1:1000)
ICC (1:200 - 1:1000)
Western blot (1:200 - 1:1000)
Specificity and Use
XRCC5 / Ku80 antibody was raised against synthetic peptide aa557-570, HEDGPTAKKLKTEQ, corresponding to Human Ku80 (BSA). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey (100%); Marmoset (93%).
Recognizes Ku80 at 82.6kD. Species cross-reactivity: Human and rodent.
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Western Blot: 1:200-1:1000 (ECL). Immunohistochemistry: Frozen sections. Not tested for paraffin. 1:200-1:1000. Immunocytochemistry: 1:200-1:1000.
PBS, pH 7.2, 40% glycerol. No preservative added.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
XRCC5 Antibody, 86 kDa subunit of Ku antigen Antibody, CTC85 Antibody, CTCBF Antibody, DNA repair protein XRCC5 Antibody, G22P2 Antibody, KARP-1 Antibody, Ku autoantigen, 80kDa Antibody, NFIV Antibody, KARP1 Antibody, Ku86 Antibody, KUB2 Antibody, TLAA Antibody, Nuclear factor IV Antibody, KU80 Antibody, Thyroid-lupus autoantigen Antibody
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.