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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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XRCC5 / Ku80 Antibody (aa557‑570) LS‑C16168
Ku80 antibody LS-C16168 is an unconjugated rabbit polyclonal antibody to human Ku80 (XRCC5). Validated for ELISA, ICC, IHC and WB.
Antibody
Catalog
Size
Price
LS-C16168-50
50 µg
$375

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Product Description

Ku80 antibody LS-C16168 is an unconjugated rabbit polyclonal antibody to human Ku80 (XRCC5). Validated for ELISA, ICC, IHC and WB.
About XRCC5 / Ku80
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. P13010 NM_021141 NP_066964.1

XRCC5 Antibody, 86 kDa subunit of Ku antigen Antibody, CTC85 Antibody, CTCBF Antibody, DNA repair protein XRCC5 Antibody, G22P2 Antibody, KARP-1 Antibody, Ku autoantigen, 80kDa Antibody, NFIV Antibody, KARP1 Antibody, Ku86 Antibody, KUB2 Antibody, TLAA Antibody, Nuclear factor IV Antibody, KU80 Antibody, Thyroid-lupus autoantigen Antibody


Specifications

Target
Human XRCC5 / Ku80
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen (1:200 - 1:1000)
  • ICC (1:200 - 1:1000)
  • Western blot (1:200 - 1:1000)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
XRCC5 / Ku80 antibody was raised against synthetic peptide aa557-570, HEDGPTAKKLKTEQ, corresponding to Human Ku80 (BSA). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey (100%); Marmoset (93%).
Epitope
aa557-570
Specificity
Recognizes Ku80 at 82.6kD. Species cross-reactivity: Human and rodent.
Usage
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Western Blot: 1:200-1:1000 (ECL). Immunohistochemistry: Frozen sections. Not tested for paraffin. 1:200-1:1000. Immunocytochemistry: 1:200-1:1000.
Presentation
PBS, pH 7.2, 40% Glycerol, No preservatives added
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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