Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
XRCC5, 86 kDa subunit of Ku antigen, CTC85, CTCBF, DNA repair protein XRCC5, G22P2, KARP-1, Ku autoantigen, 80kDa, NFIV, KARP1, Ku86, KUB2, TLAA, Nuclear factor IV, KU80, Thyroid-lupus autoantigen
(tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
IHC - Frozen (1:200 - 1:1000)
ICC (1:200 - 1:1000)
Western blot (1:200 - 1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
XRCC5 / Ku80 antibody was raised against synthetic peptide aa557-570, HEDGPTAKKLKTEQ, corresponding to Human Ku80 (BSA). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey (100%); Marmoset (93%).
Recognizes Ku80 at 82.6kD. Species cross-reactivity: Human and rodent.
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Western Blot: 1:200-1:1000 (ECL). Immunohistochemistry: Frozen sections. Not tested for paraffin. 1:200-1:1000. Immunocytochemistry: 1:200-1:1000.
PBS, pH 7.2, 40% Glycerol, No preservatives added
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.