Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 3241C1a] (IgG1) to Human XRCC5 / Ku80
ICC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, Dot Blot
Rabbit Polyclonal to Human XRCC5 / Ku80
Human, Mouse, Rat, Hamster
Human XRCC5 / Ku80
Human, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Western blot (1:500)
Specificity and Use
XRCC5 / Ku80 antibody was raised against a synthetic peptide corresponding to residues 419-440 LVYVQLPFMEDLRQYMFSSLKN] of the 80 kD Ku80 protein Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bat, Horse, Rabbit (100%); Panda, Pig (95%); Dog, Bovine, Xenopus (91%); Opossum (86%); Turkey, Chicken (82%).
Reacts with residues 419-440 [LVYVQLPFMEDLRQYMFSSLKN] of the 80 kD Ku80 protein. Sequence is 100% conserved between human, mouse, rat and hamster.
PBS, 0.02% sodium azide
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
XRCC5 Antibody, 86 kDa subunit of Ku antigen Antibody, CTC85 Antibody, CTCBF Antibody, DNA repair protein XRCC5 Antibody, G22P2 Antibody, KARP-1 Antibody, Ku autoantigen, 80kDa Antibody, NFIV Antibody, KARP1 Antibody, Ku86 Antibody, KUB2 Antibody, TLAA Antibody, Nuclear factor IV Antibody, KU80 Antibody, Thyroid-lupus autoantigen Antibody
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.