Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
XRCC5 Antibody, 86 kDa subunit of Ku antigen Antibody, CTC85 Antibody, CTCBF Antibody, DNA repair protein XRCC5 Antibody, G22P2 Antibody, KARP-1 Antibody, Ku autoantigen, 80kDa Antibody, NFIV Antibody, KARP1 Antibody, Ku86 Antibody, KUB2 Antibody, TLAA Antibody, Nuclear factor IV Antibody, KU80 Antibody, Thyroid-lupus autoantigen Antibody
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.
IHC of paraffin-embedded Cal27 Xenograft using Ku80 (XRCC5) antibody at 1:100 dilution.
Immunofluorescence of methanol-fixed HeLa using Ku80 (XRCC5) antibody at 1:200 dilution.
Ku80 antibody [N3C2], Internal detects XRCC5 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. C. 30 ug HeLa whole cell lysate/extract. D. 30 ug HepG2 whole cell lysate/extract. 7.5 % SDS-PAGE. Ku80 antibody [N3C2], Internal dilution:1:1000.
Ku80 (XRCC5) antibody immunoprecipitates Ku80 protein in IP experiments. IP Sample:1000 ug HeLa whole cell lysate/extract A. 40 ug HeLa whole cell lysate/extract B. Control with 2.5 ug of preimmune rabbit IgG C. Immunoprecipitation of Ku80 protein by 2.5 ug of Ku80 antibody 7.5% SDS-PAGE The immunoprecipitated Ku80 protein was detected by Ku80 antibody diluted at 1:1000. EasyBlot anti-rabbit IgG (anti-rabbit IgG (HRP) -01) was used as a secondary reagent.