The Immunohistochemistry Antibody Company
|Human, Mouse, Bovine (tested or 100% immunogen sequence identity)|
|Monkey, Dog, Guinea pig (at least 90% immunogen sequence identity)|
|XRCC3 antibody was raised against synthetic peptide located between aa122-171 of human XRCC3 (O43542, NP_005423). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey (100%); Marmoset, Dog, Guinea pig (92%); Bovine (83%); Mouse (78%).|
|Lyophilized from PBS with 2% sucrose|
|Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.|
|For research use only.|
XRCC3 Antibody, DNA repair protein XRCC3 Antibody, CMM6 AntibodyInvolved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD21 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, CX3 acts downstream of RAD51 recruitment; the complex binds predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junctions of replication forks.