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XRCC3 Antibody (aa122‑171) LS‑C145307
XRCC3 antibody LS-C145307 is an unconjugated rabbit polyclonal antibody to XRCC3 from human, mouse and bovine. Validated for WB.
Catalog
Size
Price
LS-C145307-50
50 µg
Unavailable

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Product Description

XRCC3 antibody LS-C145307 is an unconjugated rabbit polyclonal antibody to XRCC3 from human, mouse and bovine. Validated for WB.
About XRCC3
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD21 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, CX3 acts downstream of RAD51 recruitment; the complex binds predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junctions of replication forks. O43542 NM_005432 NP_005423.1

XRCC3 Antibody, DNA repair protein XRCC3 Antibody, CMM6 Antibody


Specifications

Target
Human XRCC3
Host
Rabbit
Reactivity
Human, Mouse, Bovine (tested or 100% immunogen sequence identity)
Predicted
Monkey, Dog, Guinea pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
XRCC3 antibody was raised against synthetic peptide located between aa122-171 of human XRCC3 (O43542, NP_005423). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey (100%); Marmoset, Dog, Guinea pig (92%); Bovine (83%); Mouse (78%).
Blocking Peptide
LS-E22408 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C145307. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa122-171
Specificity
Human XRCC3
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

XRCC3 antibody LS-C145307 Western blot of ACHN Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
XRCC3 antibody LS-C145307 Western blot of ACHN Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

XRCC3 antibody LS-C145307 Western blot of ACHN Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
XRCC3 antibody LS-C145307 Western blot of ACHN Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

XRCC3 antibody LS-C145307 Western blot of ACHN Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
XRCC3 antibody LS-C145307 Western blot of ACHN Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

XRCC3 antibody LS-C145307 Western blot of ACHN Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
XRCC3 antibody LS-C145307 Western blot of ACHN Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/25/2018

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