Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Rabbit Polyclonal to Human XRCC1
Human (tested or 100% immunogen sequence identity)
Specificity and Use
XRCC1 antibody was raised against a synthetic peptide mapping to a region between residues Ser 518, Thr 519 and Thr 523 of human X-ray Repair Complementing protein 1 using the numbering given in SwissProt entry P18887 (GeneID 7515).
Specific for human XRCC1 protein phosphorylated at residues (Ser518, Thr519, Thr523).
Suitable for use in Western Blot.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
XRCC1 Antibody, RCC Antibody, DNA repair protein XRCC1 Antibody
XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.