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XRCC1

X-ray repair complementing defective repair in Chinese hamster cells 1

XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 1
Synonyms: XRCC1, RCC, DNA repair protein XRCC1
Target Sequences: NM_006297 NP_006288.2 P18887

☰ Filters
Antibodies (51)
Proteins (5)
ELISA Kits (1)
Cell-Based (1)
Over-Expression Lysate (2)
Primary (51)
Recombinant (3)
XRCC1 (57)
Human (49)
Mouse (13)
Rat (14)
Chimpanzee (3)
Guinea pig (1)
Horse (1)
Monkey (5)
Pig (1)
Rabbit (1)
IHC (34)
IHC-P (8)
WB (48)
Flo (11)
ELISA (10)
ICC (7)
IF (18)
IP (7)
Peptide-ELISA (2)
PMA (2)
rabbit (29)
mouse (22)
IgG (19)
IgG1 (15)
IgG2b (6)
monoclonal mc (22)
polyclonal pc (29)
33-2-5 (1)
OTI2D8 (2)
OTI2E8 (2)
OTI2F8 (2)
OTI2G8 (2)
OTI2H8 (2)
OTI3C3 (2)
UMAB40 (2)
96-Well Microplate (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
Carrier-free (7)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (38)
aa407-435 (7)
aa486-535 (4)
pSer461 (2)
pSer485 / pThr488 (2)
pSer518 / pThr519/523 (2)
490-570 aa, C-terminal (1)
C-Terminus (1)
Gly552 (1)
aa15-34 (1)
aa517-566 (1)
aa600-C-term (1)
No (57)
Adherent Cell Cultures (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
XRCC1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC1.
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XRCC1 Mouse anti-Human Monoclonal (OTI2G8) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
XRCC1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC1.
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XRCC1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2G8) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
XRCC1 Antibody - Immunohistochemical staining of paraffin-embedded Kidney tissue using anti- mouse monoclonal antibody. (Dilution 1:50).
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XRCC1 Mouse anti-Human Monoclonal (OTI2F8) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
XRCC1 Antibody - Immunohistochemical staining of paraffin-embedded Kidney tissue using anti- mouse monoclonal antibody. (Dilution 1:50).
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XRCC1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2F8) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
XRCC1 Antibody - XRCC1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skin carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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XRCC1 Rabbit anti-Human Polyclonal (aa407-435) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
XRCC1 Antibody - Immunohistochemical staining of paraffin-embedded human thyroid using anti-XRCC1 clone UMAB40 mouse monoclonal antibody  at 1:50 with Polink2 Broad HRP DAB detection kit; heat-induced epitope retrieval with GBI TEE pH9.0 HIER buffer using pressure chamber for 3 minutes at 110C. Nuclear staining is seen in epithelial cells.
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XRCC1 Mouse anti-Human Monoclonal (UMAB40) Antibody
Human, Monkey
IF, IHC, PMA, WB
Unconjugated
100 µl/$493
XRCC1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of lung tissue using anti-XRCC1 mouse monoclonal antibody.  dilution 1:50; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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XRCC1 Mouse anti-Human Monoclonal (Carrier-free) (UMAB40) Antibody
Human, Monkey
IF, IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
XRCC1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-XRCC1 mouse monoclonal antibody. (Dilution 1:50).
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XRCC1 Mouse anti-Human Monoclonal (OTI2D8) Antibody
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
XRCC1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-XRCC1 mouse monoclonal antibody. (Dilution 1:50).
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XRCC1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2D8) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Select
XRCC1 Rabbit anti-Human Polyclonal (aa407-435) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
Select
XRCC1 Rabbit anti-Human Polyclonal (aa407-435) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
Select
XRCC1 Rabbit anti-Human Polyclonal (aa407-435) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Select
XRCC1 Rabbit anti-Human Polyclonal (aa407-435) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Select
XRCC1 Rabbit anti-Human Polyclonal (aa407-435) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
XRCC1 Rabbit anti-Human Polyclonal (aa407-435) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
XRCC1 Antibody - IHC analysis of XRCC1 using anti-XRCC1 antibody. XRCC1 was detected in frozen section of mouse intestine tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-XRCC1 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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XRCC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
XRCC1 Antibody - XRCC1 antibody. IHC(P): Human Breast Cancer Tissue.
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XRCC1 Rabbit anti-Human Polyclonal (aa15-34) Antibody
Rabbit, Mouse, Guinea pig, Pig, Horse, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
XRCC1 Antibody - Immunofluorescence staining of XRCC1 in U251MG cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human XRCC1 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
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XRCC1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IP, WB
Unconjugated
100 µl/$412
XRCC1 Antibody - Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody.
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XRCC1 Mouse anti-Human Monoclonal (33-2-5) Antibody
Rat, Human
IF, IHC, IP, WB
Unconjugated
0.1 ml/$303; 0.5 ml/$573; 1 ml/$901
XRCC1 Protein - 12.5% SDS-PAGE of human XRCC1 stained with Coomassie Blue
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Wheat Germ Extract
GST
95.37 kDa
10 µg/$479; 25 µg/$670
XRCC1 Antibody - Detection of Human Phospho XRCC1 (S518/T519/T523) by Immunohistochemistry. Samples: FFPE serial sections of human breast adenocarcinoma. Mock phosphatase treated section (left) or calf intestinal phosphatase-treated section (right) immunostained for Phospho XRCC1 (S518/T519/T523). Antibody: Affinity purified rabbit anti-Phospho XRCC1 (S518/T519/T523) used at a dilution of 1:250.
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XRCC1 Rabbit anti-Human Polyclonal (pSer518 / pThr519/523) Antibody
Mouse, Human
IF, IHC
Unconjugated
0.5 µg/$295; 100 µl/$554
XRCC1 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using XRCC1 Antibody. The picture on the right is blocked with the synthesized peptide.
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XRCC1 Rabbit anti-Human Polyclonal (aa517-566) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
XRCC1 Antibody - Western blot of XRCC1 antibody
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XRCC1 Rabbit anti-Human Polyclonal (490-570 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
XRCC1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using XRCC1 antibody.
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XRCC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
XRCC1 Antibody - Anti-XRCC1 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY XRCC1.
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XRCC1 Mouse anti-Human Monoclonal (OTI2E8) Antibody
IF, WB
Unconjugated
100 µl/$434
Viewing 1-25 of 57 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).