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Anti-XRCC1 Antibody (clone 33-2-5) LS-C95522

Catalog Size Price
LS-C95522-0.5 0.5 ml Unavailable
LS-C95522-1 1 ml Unavailable

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Anti-XRCC1 Antibody (aa407-435, AP) LS-C273735
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100% Guaranteed
Mouse Monoclonal [clone 33-2-5] (IgG2b) to Human XRCC1
Human, Rat
IHC, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated

Details

Human XRCC1
Mouse
Human, Rat (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [33-2-5]
Unconjugated
Ig fraction
Unmodified

Applications

  • IHC
  • Immunofluorescence
  • Western blot
  • Immunoprecipitation

Specificity and Use

XRCC1 antibody was raised against bALB/C mice were injected with recombinant human XRCC1 protein.
Is specific to the 85kD kD protein known as XRCC1. X-ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. It binds to DNS ligase III through C-terminal 96 amino acids and to DNA polymerase-beta through the N-terminal half. XRCC1 is expressed at high levels in testis. This antibody cross reacts with rat.

Packaging

0.05% sodium azide
Store at 2-8°C. Do not freeze.
For research use only.

About XRCC1

P18887 NM_006297 NP_006288.2

XRCC1 Antibody, RCC Antibody, DNA repair protein XRCC1 Antibody

XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody LS-C95522.

Requested From: 
Date Requested: 8/23/2017

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