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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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XRCC1 Antibody (clone 33‑2‑5) LS‑C95522
XRCC1 antibody LS-C95522 is an unconjugated mouse monoclonal antibody to XRCC1 from human and rat. Validated for IF, IHC, IP and WB.
Catalog
Size
Price
LS-C95522-0.5
0.5 ml
Unavailable
LS-C95522-1
1 ml
Unavailable

Popular XRCC1 Products

Formalin-fixed, paraffin-embedded human testis stained with peroxidase-conjugate and AEC chromogen. Note nuclear staining of spermatocytes. This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC1.
Species: Human
Applications: Western blot, Flow Cytometry
Immunohistochemical staining of paraffin-embedded bladder tissue using anti- mouse monoclonal antibody. (Dilution 1:50).
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Anti-XRCC1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8524 dilution 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Anti-XRCC1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8620 dilution 10 ug/ml.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation

Product Description

XRCC1 antibody LS-C95522 is an unconjugated mouse monoclonal antibody to XRCC1 from human and rat. Validated for IF, IHC, IP and WB.
About XRCC1
XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. P18887 NM_006297 NP_006288.2

XRCC1 Antibody, RCC Antibody, DNA repair protein XRCC1 Antibody


Specifications

Target
Human XRCC1
Host
Mouse
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal [33-2-5]
Conjugations
Unconjugated
Purification
Ig fraction
Modifications
Unmodified
Applications
  • IHC
  • Immunofluorescence
  • Western blot
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
XRCC1 antibody was raised against bALB/C mice were injected with recombinant human XRCC1 protein.
Specificity
Is specific to the 85kD kD protein known as XRCC1. X-ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. It binds to DNS ligase III through C-terminal 96 amino acids and to DNA polymerase-beta through the N-terminal half. XRCC1 is expressed at high levels in testis. This antibody cross reacts with rat.
Presentation
0.05% sodium azide
Storage
Store at 2-8°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody LS-C95522.
Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody LS-C95522.

Immunohistochemistry

Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody LS-C95522.
Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody LS-C95522.

Immunohistochemistry

Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody LS-C95522.
Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody LS-C95522.

Immunohistochemistry

Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody LS-C95522.
Formalin-fixed, paraffin-embedded human testis stained with XRCC-1 antibody LS-C95522.


Requested From: 
Date Requested: 6/20/2018

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