XPO4 / Exportin 4

exportin 4

Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

☰ Filters

Products

Antibodies (4)

Proteins (1)

Type

Primary (4)

Recombinant (1)

Target

XPO4 / Exportin 4 (5)

Reactivity

Human (4)

Mouse (3)

Rat (3)

Bovine (1)

Chicken (1)

Dog (1)

Monkey (1)

Xenopus (1)

Zebrafish (1)

Application

IHC (1)

WB (4)

IF (1)

Peptide-ELISA (1)

Host

rabbit (4)

Isotype

IgG (4)

Clonality

polyclonal pc (4)

Format

Unconjugated (4)

Epitope

C-Terminus (1)

aa850-950 (1)

Publications

No (5)

Tag

His, N-Terminal (1)

Species

Human (1)

Source

E. coli (1)

Select

XPO4 / Exportin 4 Antibody LS-C807049

Antibody:

XPO4 / Exportin 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

XPO4 / Exportin 4 Antibody LS-C750473

Antibody:

XPO4 / Exportin 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

XPO4 / Exportin 4 Antibody (aa850-950) LS-C47285

Antibody:

XPO4 / Exportin 4 Rabbit anti-Human Polyclonal (aa850-950) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Mouse, Dog, Bovine, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$386

Select

XPO4 / Exportin 4 Antibody (C-Terminus) LS-C357876

Antibody:

XPO4 / Exportin 4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

25 µg/$364; 100 µg/$511

Select

Human XPO4 / Exportin 4 Protein (Recombinant His, N-Terminal) (Ala881-Lys1151) - LS-G133175

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

34.3kDa

Price:

10 µg/$299; 50 µg/$552; 200 µg/$1,080; 100 µg/$882; 1 mg/$2,261; 500 µg/$1,775; 5 mg/$3,851; 2 mg/$2,453

Viewing 1-5 of 5 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.