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Anti-XIAP Antibody (C-Terminus) LS-C18565

Catalog	Size	Price
LS-C18565-100	100 µg	Unavailable

Related Products

69 XIAP Antibodies

Most Popular XIAP Antibodies

Anti-XIAP Antibody (C-Terminus) IHC-plus™ LS-B702

Antibody:	Rabbit Polyclonal (IgG) to Human XIAP
Reactivity:	Human, Mouse
Application:	IHC, IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-XIAP antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B702 concentration 2 ug/ml.

Anti-XIAP Antibody LS-C48229

Antibody:	Rabbit Polyclonal to Human XIAP
Reactivity:	Human, Mouse, Rat
Application:	IHC, Western blot, Immunoprecipitation
Format:	Unconjugated

Anti-XIAP Antibody (aa1-30) LS-C100373

Antibody:	Rabbit Polyclonal to Human XIAP
Reactivity:	Human, Mouse
Application:	IHC, IHC - Paraffin, Western blot
Format:	Unconjugated

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with BIRC4 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-XIAP Antibody IHC-plus™ LS-B4870

Antibody:	Rabbit Polyclonal to Human XIAP
Reactivity:	Human
Application:	IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Format:	Unconjugated

Anti-XIAP antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4870 concentration 10 ug/ml.

Anti-XIAP Antibody (aa163-230) LS-C148307

Antibody:	Rabbit Polyclonal to Human XIAP
Reactivity:	Human, Mouse, Rat, Gerbil
Application:	IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Format:	Unconjugated

IHC of XIAP in formalin-fixed, paraffin-embedded human breast carcinoma using LS-C148307 at 1:2000. A-A3, successively higher magnifications of the breast carcinoma tissue section. Hematoxylin-Eosin counterstain.

Antibody:	Rabbit Polyclonal to Human XIAP
Reactivity:	Human, Mouse
Application:	IHC, IHC - Paraffin, IHC - Frozen, Western blot (applications tested for the base form of this product only)
Format:	Unconjugated

Details

Target:	Human XIAP
Host:	Rabbit
Reactivity:	Human, Mouse (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated. Also available conjugated with AP, Biotin, FITC, HRP, PE.
Purification:	Affinity purified
Modifications:	Unmodified

Applications

Approved:

IHC
IHC - Paraffin
IHC - Frozen
Western blot (0.5 - 2 µg/ml)
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:	XIAP antibody was raised against synthetic peptide corresponding to a thirteen amino acid sequence with the C-terminal region of human XIAP.
Epitope:	C-Terminus
Specificity:	Specific for human X-chromosome linked inhibitor of apoptosis (XIAP). Detects a band of approximately 57kD in human kidney lysates. Species cross-reactivity: Mouse.
Usage:	Suitable for use in Western Blot. and Immunohistochemistry (Frozen and paraffin). Western Blot: 0.5-2.0 ug/ml. Immunohistochemistry (paraffin): 2 ug/ml, Requires antigen retrieval using heat treatment prior to staining of paraffin sections.

Packaging

Presentation:	PBS, pH 7.4, 0.02% sodium azide.
Storage:	Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions:	For research use only.

About XIAP

Uniprot: P98170 NCBI: NM_001167 NP_001158.2

Synonyms: XIAP Antibody, API3 Antibody, BIRC4 Antibody, HILP Antibody, IAP-like protein Antibody, IAP3 Antibody, HIAP-3 Antibody, HIAP3 Antibody, IAP-3 Antibody, ILP Antibody, ILP1 Antibody, MIHA Antibody, X-linked IAP Antibody, XLP2 Antibody

Description: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state.

(More About XIAP)

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Date Requested: 4/21/2018

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