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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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WWTR1 / TAZ Antibody (aa386‑400) IHC‑plus™ LS‑B94 Best Seller
Note: This antibody replaces LS-C2914, LS-C39555
TAZ antibody LS-B94 is an unconjugated rabbit polyclonal antibody to human TAZ (WWTR1). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Catalog
Size
Price
LS-B94-100
100 µg (1 mg/ml)
Unavailable

Popular WWTR1 / TAZ Products

Detection of protein in HEK 293 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: Western blot, Immunoprecipitation
WWTR1 Antibody western blot of 293 cell line lysates (35 ug/lane). The WWTR1 antibody detected the WWTR1 protein (arrow).
Species: Human
Applications: Western blot
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Anti-WWTR1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY WWTR1.
Species: Human, Monkey, Mouse, Dog
Applications: Immunofluorescence, Western blot, Flow Cytometry

Product Description

TAZ antibody LS-B94 is an unconjugated rabbit polyclonal antibody to human TAZ (WWTR1). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
About WWTR1 / TAZ
Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Q9GZV5 NM_015472 NP_056287.1

WWTR1 Antibody


Specifications

Target
Human WWTR1 / TAZ
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
WWTR1 / TAZ antibody was raised against synthetic peptide representing residues 386-400 of the human TAZ protein
Epitope
aa386-400
Specificity
Reacts with residues 386-400, which is the PDZ-binding domain of the 49kD human TAZ protein.
Usage
Immunohistochemistry: LS-B94 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B94 was determined to be 2.5 ug/ml.
Presentation
PBS, 0.02% sodium azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Willin, an upstream component of the hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts. Moleirinho S, Patrick C, Tilston-L[Character fc]nel AM, Higginson JR, Angus L, Antkowiak M, Barnett SC, Prystowsky MB, Reynolds PA, Gunn-Moore FJ. PloS one. 2013 8:e60028. [Full Text Article] [PubMed:23593160] [PMC:PMC3620498]

Customer Reviews (0)


Images

Immunohistochemistry

Anti-WWTR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B94 concentration 5 ug/ml.
Anti-WWTR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B94 concentration 5 ug/ml.

Immunohistochemistry

Anti-WWTR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B94 concentration 5 ug/ml.
Anti-WWTR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B94 concentration 5 ug/ml.

Immunohistochemistry

Anti-WWTR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B94 concentration 5 ug/ml.
Anti-WWTR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B94 concentration 5 ug/ml.

Immunohistochemistry

Anti-WWTR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B94 concentration 5 ug/ml.
Anti-WWTR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B94 concentration 5 ug/ml.

Requested From: 
Date Requested: 7/15/2018

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