WWP2

WW domain containing E3 ubiquitin protein ligase 2

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.

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Products

Antibodies (38)

Proteins (11)

ELISA Kits (1)

Type

Over-Expression Lysate (4)

Primary (38)

Recombinant (7)

Sandwich (1)

Target

WWP2 (50)

Reactivity

Human (39)

Mouse (10)

Rat (10)

Bat (6)

Bovine (9)

Chimpanzee (9)

Dog (12)

Gibbon (12)

Guinea pig (9)

Hamster (9)

Horse (6)

Monkey (12)

Orangutan (12)

Pig (6)

Rabbit (9)

Xenopus (3)

Zebrafish (9)

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Application

IHC (8)

IHC-P (5)

WB (32)

ELISA (7)

ICC (8)

IP (10)

Peptide-ELISA (1)

Host

rabbit (37)

mouse (1)

Isotype

IgG (22)

Clonality

monoclonal mc (1)

polyclonal pc (37)

Format

96-Well Strip Plate (1)

APC (1)

APC Conjugated (1)

Biotin Conjugated (6)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (1)

Unconjugated (16)

Epitope

C-Terminus (4)

N-Terminus (4)

aa323-372 (4)

aa395-444 (4)

aa150-200 (1)

aa200-250 (1)

aa218-252 (1)

Publications

No (50)

Sample Type

Cell Lysates (1)

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

His-GST (1)

His-T7, N-terminus (1)

Myc-DDK (Flag) (7)

Species

Human (9)

Source

293T Cells (2)

Baculovirus (1)

E. coli (1)

HEK 293 Cells (5)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

Select

WWP2 Antibody LS-C332087

Antibody:

WWP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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WWP2 Antibody LS-C660643

Antibody:

WWP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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WWP2 Antibody LS-C680044

Antibody:

WWP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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WWP2 Antibody LS-C663508

Antibody:

WWP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352

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WWP2 Antibody (HRP) LS-C714392

Antibody:

WWP2 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$351; 200 µl/$411; 500 µl/$618; 1 ml/$774; 2 ml/$1,010; 5 ml/$1,757

Select

WWP2 Antibody (Biotin) LS-C689327

Antibody:

WWP2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$329; 200 µl/$381; 500 µl/$550; 1 ml/$654; 2 ml/$890; 5 ml/$1,487

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WWP2 Antibody (FITC) LS-C696429

Antibody:

WWP2 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$362; 200 µl/$427; 500 µl/$666; 1 ml/$826; 2 ml/$1,067; 5 ml/$1,892

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WWP2 Antibody (PE) LS-C728459

Antibody:

WWP2 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

PE Conjugated

Price:

100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703

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WWP2 Antibody (Cy3) LS-C705377

Antibody:

WWP2 Rabbit anti-Human Polyclonal (Cy3) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Cy3 Conjugated

Price:

100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703

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WWP2 Antibody (APC) LS-C741752

Antibody:

WWP2 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

APC Conjugated

Price:

100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703

Select

WWP2 Antibody (APC, Cy7) LS-C737356

Antibody:

WWP2 Rabbit anti-Human Polyclonal (APC, Cy7) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$535; 200 µl/$714; 500 µl/$1,236; 1 ml/$1,545; 2 ml/$2,163; 5 ml/$4,053

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• Cy3
• APC
• More...
  • APC, Cy7

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • Cy3
  • APC
  • APC, Cy7

Select

WWP2 Antibody (N-Terminus) LS-C40407

Antibody:

WWP2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$424

Select

WWP2 Antibody (N-Terminus, HRP) LS-C444659

Antibody:

WWP2 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

WWP2 Antibody (N-Terminus, Biotin) LS-C444655

Antibody:

WWP2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

WWP2 Antibody (N-Terminus, FITC) LS-C444656

Antibody:

WWP2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

WWP2 Antibody LS-C409037

Antibody:

WWP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

WWP2 Antibody (aa150-200) LS-C289644

Antibody:

WWP2 Rabbit anti-Human Polyclonal (aa150-200) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

WWP2 Antibody (aa200-250) LS-C289643

Antibody:

WWP2 Rabbit anti-Human Polyclonal (aa200-250) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

WWP2 Antibody (aa218-252) LS-C356472

Antibody:

WWP2 Rabbit anti-Human Polyclonal (aa218-252) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

WWP2 Antibody LS-C489884

Antibody:

WWP2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

WWP2 Antibody LS-C489885

Antibody:

WWP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

WWP2 Antibody LS-C771849

Antibody:

WWP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

WWP2 Antibody (aa395-444) LS-C110756

Antibody:

WWP2 Rabbit anti-Human Polyclonal (aa395-444) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

WWP2 Antibody (C-Terminus) LS-C80543

Antibody:

WWP2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

WWP2 Antibody (aa323-372) LS-C101998

Antibody:

WWP2 Rabbit anti-Human Polyclonal (aa323-372) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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