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| Catalog Number | Size | Price |
|---|---|---|
| LS-C500833-50 | 50 µg | $294 |
| LS-C500833-100 | 100 µg | $360 |
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Polyclonal Rabbit anti‑Human WTAP Antibody (IHC, IF, WB) LS‑C500833
Polyclonal Rabbit anti‑Human WTAP Antibody (IHC, IF, WB) LS‑C500833
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
WTAP antibody LS-C500833 is an unconjugated rabbit polyclonal antibody to WTAP from human. It is reactive with human, mouse and rat. Validated for ELISA, IF, IHC and WB.
Target
Human WTAP
Synonyms
WTAP | HFL(2)D | KIAA0105 | PNAS-132 | WT1-associated protein | Female-lethal(2)D homolog
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Pre-mRNA-splicing regulator WTAP protein (1-151AA)
Specificity
Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).
Applications
- IHC
- Immunofluorescence
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About WTAP
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Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Species:
Human, Mouse
Applications:
IHC, Western blot, ELISA
Reactivity:
All species
Range:
123.5-10000 pg/ml
Reactivity:
Mouse
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
