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Human WT1 / Wilms Tumor 1 | |
Rabbit | |
Human (tested or 100% immunogen sequence identity) | |
Monkey (at least 90% immunogen sequence identity) | |
IgG Polyclonal | |
Unconjugated. Also available conjugated with Biotin, FITC, HRP. | |
Immunoaffinity purified | |
Unmodified |
Synthetic peptide from N-Terminus of human WT1 (NP_000369). Percent identity by BLAST analysis: Human (100%); Gorilla, Marmoset (92%). | ||
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N-Terminus | ||
Human WT1 | ||
Western Blot: Suggested dilution at 1µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:312500. |
Lyophilized from PBS with 2% sucrose | |
Distilled water | |
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles. | |
For research use only. |
WT1 Antibody, GUD Antibody, EWS-WT1 Antibody, Amino-terminal domain of EWS Antibody, WAGR Antibody, WIT-2 Antibody, Wilms tumor protein Antibody, AWT1 Antibody, Wilms tumor 1 Antibody, WT33 Antibody, NPHS4 Antibody
WT1 / Wilms Tumor 1 is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues.
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