Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human WT1 / Wilms Tumor 1
IHC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Goat Polyclonal to Human WT1 / Wilms Tumor 1
Western blot, ELISA
Human WT1 / Wilms Tumor 1
Human (tested or 100% immunogen sequence identity)
Mouse, Rat (at least 90% immunogen sequence identity)
Western blot (1:4000) & (1 - 3 µg/ml)
IHC - Paraffin
Specificity and Use
Synthetic peptide QDPASTCVPEPASQH from the N-terminus of human WT1 (NP_000369.3; NP_077742.2; NP_077743.2; NP_077744.3). Percent identity with other species by BLAST analysis: Human (100%), Mouse (93%), Rat (93%), Marmoset (87%), Monkey (80%).
LS-E26134 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55689. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human WT1. This antibody is expected to recognise all four reported isoforms (NP_000369.3, NP_077742.2, NP_077743.2, NP_077744.3).
WT1 / Wilms Tumor 1 is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues.