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WNT4

wingless-type MMTV integration site family, member 4

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.

Gene Name: wingless-type MMTV integration site family, member 4
Family/Subfamily: WNT , not assigned-WNT
Synonyms: WNT4, WNT-4, Protein Wnt-4, SERKAL
Target Sequences: NM_030761 NP_110388.2 P56705

Publications (1)

1
Expression of wnt4/5 during reproductive cycle of catfish and wnt5 promoter analysis. Prathibha Y, Senthilkumaran B. The Journal of endocrinology. 2017 232:1-13. (WB; Chicken, Human) [Full Text Article] [PubMed:27875264] Related Antibodies: LS-C109642.

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Antibodies (46)
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WNT4 Antibody - Anti-WNT4 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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WNT4 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
WNT4 Antibody - Anti-WNT4 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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WNT4 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
WNT4 Antibody - WNT4 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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WNT4 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
WNT4 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
WNT4 Antibody - Anti-WNT4 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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WNT4 Rabbit anti-Human Polyclonal (aa242-269) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$440
WNT4 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$902
WNT4 Antibody - Formalin-fixed and paraffin-embedded human bladder carcinoma reacted with WNT4 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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WNT4 Rabbit anti-Human Polyclonal (aa211-239) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$393
WNT4 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
WNT4 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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WNT4 Rat anti-Mouse Monoclonal (aa37-76) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$896
WNT4 Antibody
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WNT4 Mouse anti-Human Monoclonal Antibody
Human
ICC, WB
Unconjugated
100 µl/$324; 200 µl/$373; 500 µl/$535; 1 ml/$626; 2 ml/$859; 5 ml/$1,421
WNT4 Antibody
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WNT4 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ICC, IP, WB
HRP Conjugated
100 µl/$358; 200 µl/$422; 500 µl/$651; 1 ml/$811; 2 ml/$1,049; 5 ml/$1,848
WNT4 Antibody
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WNT4 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ICC, IP, WB
Biotin Conjugated
100 µl/$335; 200 µl/$389; 500 µl/$568; 1 ml/$688; 2 ml/$925; 5 ml/$1,564
WNT4 Antibody
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WNT4 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ICC, IP, WB
FITC Conjugated
100 µl/$370; 200 µl/$438; 500 µl/$700; 1 ml/$859; 2 ml/$1,107; 5 ml/$1,991
WNT4 Antibody
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WNT4 Mouse anti-Human Monoclonal (APC) Antibody
Human
ICC, IP, WB
APC Conjugated
100 µl/$438; 200 µl/$535; 500 µl/$952; 1 ml/$1,124; 2 ml/$1,516; 5 ml/$2,843
WNT4 Antibody
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WNT4 Mouse anti-Human Monoclonal (APC, Cy7) Antibody
Human
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$551; 200 µl/$751; 500 µl/$1,300; 1 ml/$1,625; 2 ml/$2,275; 5 ml/$4,264
WNT4 Antibody
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WNT4 Mouse anti-Human Monoclonal (PE) Antibody
Human
ICC, IP, WB
PE Conjugated
100 µl/$438; 200 µl/$535; 500 µl/$952; 1 ml/$1,124; 2 ml/$1,516; 5 ml/$2,843
WNT4 Antibody
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WNT4 Mouse anti-Human Monoclonal (Cy3) Antibody
Human
ICC, IP, WB
Cy3 Conjugated
100 µl/$438; 200 µl/$535; 500 µl/$952; 1 ml/$1,124; 2 ml/$1,516; 5 ml/$2,843
WNT4 Antibody - Immunohistochemistry of paraffin-embedded human testis using antibody at dilution of 1:100.
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WNT4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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WNT4 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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WNT4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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WNT4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
WNT4 Protein - 12.5% SDS-PAGE of human WNT4 stained with Coomassie Blue
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Wheat Germ Extract
GST
65.5 kDa
2 µg/$439
WNT4 ELISA Kit
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Sandwich
96-Well Microplate
Human
1.23 - 300 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$700
WNT4 Antibody - WNT4 antibody immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml), showing vesicle staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
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WNT4 Goat anti-Human Polyclonal (aa23-36) Antibody
Xenopus, Chicken, Zebrafish, Pig, Mouse, Rat, Human, Monkey
IF, Peptide-ELISA, WB
Unconjugated
100 µg/$503
Viewing 1-25 of 64 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).