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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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WNT16 Antibody (Internal) IHC‑plus™ LS‑A9630
WNT16 antibody LS-A9630 is an unconjugated rabbit polyclonal antibody to human WNT16. Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Catalog
Size
Price
LS-A9630-50
50 µg (1 mg/ml)
Unavailable
In Stock for Immediate Shipment

Popular WNT16 Products

Anti-WNT16 antibody LS-A9629 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Mouse, Rat, Hamster
Applications: IHC, IHC - Paraffin
WNT16 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Anti-WNT16 antibody LS-A9629 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Mouse, Rat, Hamster
Applications: IHC, IHC - Paraffin

Product Description

WNT16 antibody LS-A9630 is an unconjugated rabbit polyclonal antibody to human WNT16. Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
About WNT16
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. Q9UBV4 NM_016087 NP_057171.2

WNT16 Antibody, Protein Wnt-16 Antibody


Specifications

Target
Human WNT16
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
WNT16 antibody was raised against synthetic 15 amino acid peptide from internal region of human WNT16. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Bovine, Horse (93%); Hamster, Elephant, Pig (87%); Mouse, Rat, Panda, Dog, Bat, Rabbit, Lizard (80%).
Blocking Peptide
LS-E29720 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A9630. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Internal
Specificity
Human WNT16. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, less than 0.1% sodium azide.
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (3)

1
WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway. Binet R, Ythier D, Robles AI, Collado M, Larrieu D, Fonti C, Brambilla E, Brambilla C, Serrano M, Harris CC, Pedeux R. Cancer research. 2009 Dec;69:9183-91. [Full Text Article] [PubMed:19951988]
2
Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis. Wiel C, Augert A, Vincent DF, Gitenay D, Vindrieux D, Le Calv[Character e9] B, Arfi V, Lallet-Daher H, Reynaud C, Treilleux I, Bartholin L, Lelievre E, Bernard D. Cell death & disease. 2013 4:e855. [Full Text Article] [PubMed:24113189] [PMC:PMC3824691]
3
Carriers of a novel frame-shift insertion in WNT16a possess elevated pancreatic expression of TCF7L2. Howard EW, Been LF, Lerner M, Brackett D, Lightfoot S, Bullen EC, Sanghera DK. BMC genetics. 2013 14:28. (IHC; Human) [Full Text Article] [PubMed:23617586] [PMC:PMC3675375]

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Images


Immunohistochemistry

Anti-WNT16 antibody LS-A9630 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-WNT16 antibody LS-A9630 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-WNT16 antibody LS-A9630 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-WNT16 antibody LS-A9630 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-WNT16 antibody LS-A9630 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-WNT16 antibody LS-A9630 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-WNT16 antibody LS-A9630 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-WNT16 antibody LS-A9630 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.


Requested From: 
Date Requested: 6/25/2018

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