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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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WNK4 Antibody (aa200‑300, DY550) LS‑C142345
WNK4 antibody LS-C142345 is a DY550-conjugated rabbit polyclonal antibody to WNK4 from human and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C142345-100
100 µl
Unavailable

Popular WNK4 Products

Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, Western blot
Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Species: Human
Applications: IHC, Immunofluorescence, ELISA

Product Description

WNK4 antibody LS-C142345 is a DY550-conjugated rabbit polyclonal antibody to WNK4 from human and rat. Validated for IHC and WB.
About WNK4
Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, SGK1, TRPV5 and TRPV6. Regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation which appears to prevent membrane trafficking of SLC12A3. Q96J92 NM_032387 NP_115763.2

WNK4 Antibody, PHA2B Antibody, PRKWNK4 Antibody


Specifications

Target
Human WNK4
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
DyLight 550. Also available conjugated with Biotin, DY650, DY488.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot (2 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
WNK4 antibody was raised against a synthetic peptide sequence made to a region of the human protein between residues 200-300. Percent identity by BLAST analysis: Rat (100%).
Epitope
aa200-300
Specificity
WNK4 protein.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of WNK4 in mouse kidney lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of WNK4 in mouse kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of WNK4 in mouse kidney lysate using LS-2942.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of WNK4 in mouse kidney lysate using LS-2942. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of WNK4 in mouse kidney lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of WNK4 in mouse kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of WNK4 in mouse kidney lysate using LS-2942.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of WNK4 in mouse kidney lysate using LS-2942. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of WNK4 in mouse kidney lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of WNK4 in mouse kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of WNK4 in mouse kidney lysate using LS-2942.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of WNK4 in mouse kidney lysate using LS-2942. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Adrenal Cortex: Formalin-Fixed Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of WNK4 in mouse kidney lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of WNK4 in mouse kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of WNK4 in mouse kidney lysate using LS-2942.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of WNK4 in mouse kidney lysate using LS-2942. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/17/2018

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