WNK4

WNK lysine deficient protein kinase 4

Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, SGK1, TRPV5 and TRPV6. Regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation which appears to prevent membrane trafficking of SLC12A3. Also inhibits the renal K+ channel, KCNJ1, via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis. WNK4 appears to act as a molecular switch that can vary the balance between NaCl reabsorption and K+ secretion to maintain integrated homeostasis. Phosphorylates NEDD4L.

☰ Filters

Products

Antibodies (26)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (26)

Recombinant (2)

Target

WNK4 (30)

Reactivity

Human (26)

Mouse (11)

Rat (13)

Dog (1)

Primate (4)

Application

IHC (12)

IHC-P (5)

WB (8)

ELISA (19)

IF (1)

Host

rabbit (26)

Isotype

IgG (20)

Clonality

polyclonal pc (26)

Format

APC Conjugated (2)

Biotin Conjugated (4)

DY488 Conjugated (1)

DY550 Conjugated (1)

DY650 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (9)

Epitope

C-Terminus (6)

N-Terminus (6)

aa200-300 (5)

Internal (1)

Publications

No (30)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Select

WNK4 Antibody (aa200-300) LS-C90507

Antibody:

WNK4 Rabbit anti-Human Polyclonal (aa200-300) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$649

Select

WNK4 Antibody LS-C680029

Antibody:

WNK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

WNK4 Antibody (HRP) LS-C680031

Antibody:

WNK4 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

WNK4 Antibody (Biotin) LS-C680030

Antibody:

WNK4 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

WNK4 Antibody (FITC) LS-C680033

Antibody:

WNK4 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

WNK4 Antibody (C-Terminus) LS-C329112

Antibody:

WNK4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Primate, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

Select

WNK4 Antibody (C-Terminus, HRP) LS-C550309

Antibody:

WNK4 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

HRP Conjugated

Price:

200 µl/$952

Select

WNK4 Antibody (C-Terminus, Biotin) LS-C530226

Antibody:

WNK4 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

WNK4 Antibody (C-Terminus, FITC) LS-C246408

Antibody:

WNK4 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse, Rat, Primate, Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

Select

WNK4 Antibody (C-Terminus, APC) LS-C246407

Antibody:

WNK4 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Mouse, Rat, Primate, Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

Select

WNK4 Antibody (C-Terminus, PE) LS-C246409

Antibody:

WNK4 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Mouse, Rat, Primate, Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

WNK4 Antibody LS-C831073

Antibody:

WNK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

WNK4 Antibody (aa200-300, Biotin) LS-C142341

Antibody:

WNK4 Rabbit anti-Human Polyclonal (aa200-300) (Biotin) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

0.1 ml/$416

Select

WNK4 Antibody (aa200-300, DY488) LS-C142343

Antibody:

WNK4 Rabbit anti-Human Polyclonal (aa200-300) (DY488) Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P, WB

Format:

DY488 Conjugated

Price:

0.1 ml/$416

Select

WNK4 Antibody (aa200-300, DY550) LS-C142345

Antibody:

WNK4 Rabbit anti-Human Polyclonal (aa200-300) (DY550) Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P, WB

Format:

DY550 Conjugated

Price:

0.1 ml/$416

Select

WNK4 Antibody (aa200-300, DY650) LS-C142342

Antibody:

WNK4 Rabbit anti-Human Polyclonal (aa200-300) (DY650) Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P, WB

Format:

DY650 Conjugated

Price:

0.1 ml/$416

• Biotin
• DY488
• DY550
• DY650

• Biotin
• DY488
• DY550
• More...
  • DY650

Select

WNK4 Antibody (Internal) LS-C11071

Antibody:

WNK4 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

Select

WNK4 Antibody LS-C778783

Antibody:

WNK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

WNK4 Antibody (N-Terminus) LS-C330300

Antibody:

WNK4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

200 µl/$734

Select

WNK4 Antibody (N-Terminus, Biotin) LS-C520515

Antibody:

WNK4 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

WNK4 Antibody (N-Terminus, FITC) LS-C242757

Antibody:

WNK4 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

200 µl/$952

Select

WNK4 Antibody (N-Terminus, APC) LS-C242758

Antibody:

WNK4 Rabbit anti-Human Polyclonal (N-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

APC Conjugated

Price:

200 µl/$952

Select

WNK4 Antibody (N-Terminus, PE) LS-C242759

Antibody:

WNK4 Rabbit anti-Human Polyclonal (N-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE

Select

WNK4 Antibody LS-C132959

Antibody:

WNK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Dog, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$688

Select

WNK4 Antibody LS-C661620

Antibody:

WNK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Format:

Unconjugated

Price:

100 µg/$351

Viewing 1-25 of 30 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.