WIBG

within bgcn homolog (Drosophila)

Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA; the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC.

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Products

Antibodies (35)

Proteins (10)

Type

Over-Expression Lysate (4)

Primary (35)

Recombinant (6)

Target

WIBG (45)

Reactivity

Human (34)

Mouse (11)

Bat (3)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Horse (3)

Monkey (3)

Pig (3)

Xenopus (3)

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Application

IHC (23)

IHC-P (6)

WB (33)

ELISA (6)

IF (6)

PMA (6)

Host

rabbit (15)

mouse (20)

Isotype

IgG (6)

IgG1 (16)

IgG2a (4)

Clonality

monoclonal mc (20)

polyclonal pc (15)

Clone

OTI11C5 (2)

OTI1E10 (2)

OTI2C1 (2)

OTI2C7 (2)

OTI5E2 (2)

OTI8D7 (2)

OTI9C7 (2)

UMAB207 (2)

UMAB208 (2)

UMAB209 (2)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

Carrier-free (10)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (24)

Epitope

aa12-40 (7)

C-Terminus (4)

aa81-130 (4)

Publications

No (45)

Tag

6His, C-terminus (2)

GST (1)

His (1)

Myc-DDK (Flag) (6)

Species

Human (8)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

Select

WIBG Antibody (aa12-40) LS-C160622

Antibody:

WIBG Rabbit anti-Human Polyclonal (aa12-40) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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WIBG Antibody (clone UMAB209) LS-C796967

Antibody:

WIBG Mouse anti-Human Monoclonal (UMAB209) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA, WB

Format:

Unconjugated

Price:

100 µl/$493

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WIBG Antibody (clone UMAB208) LS-C796966

Antibody:

WIBG Mouse anti-Human Monoclonal (UMAB208) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA, WB

Format:

Unconjugated

Price:

100 µl/$493

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WIBG Antibody (clone UMAB207) LS-C796963

Antibody:

WIBG Mouse anti-Human Monoclonal (UMAB207) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA, WB

Format:

Unconjugated

Price:

100 µl/$493

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WIBG Antibody (clone UMAB209, Carrier-free) LS-C827397

Antibody:

WIBG Mouse anti-Human Monoclonal (Carrier-free) (UMAB209) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$539

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WIBG Antibody (clone UMAB208, Carrier-free) LS-C827396

Antibody:

WIBG Mouse anti-Human Monoclonal (Carrier-free) (UMAB208) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$539

Select

WIBG Antibody (clone UMAB207, Carrier-free) LS-C827395

Antibody:

WIBG Mouse anti-Human Monoclonal (Carrier-free) (UMAB207) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$539

Select

WIBG Antibody (clone OTI5E2) LS-C339981

Antibody:

WIBG Mouse anti-Human Monoclonal (OTI5E2) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

WIBG Antibody (clone OTI5E2, Carrier-free) LS-C790930

Antibody:

WIBG Mouse anti-Human Monoclonal (Carrier-free) (OTI5E2) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

WIBG Antibody (clone OTI1E10) LS-C339990

Antibody:

WIBG Mouse anti-Human Monoclonal (OTI1E10) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

WIBG Antibody (clone OTI1E10, Carrier-free) LS-C790938

Antibody:

WIBG Mouse anti-Human Monoclonal (Carrier-free) (OTI1E10) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

WIBG Antibody (clone OTI2C1) LS-C340033

Antibody:

WIBG Mouse anti-Human Monoclonal (OTI2C1) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

WIBG Antibody (clone OTI2C1, Carrier-free) LS-C790979

Antibody:

WIBG Mouse anti-Human Monoclonal (Carrier-free) (OTI2C1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

WIBG Antibody (clone OTI9C7) LS-C339988

Antibody:

WIBG Mouse anti-Human Monoclonal (OTI9C7) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$434

Select

WIBG Antibody (clone OTI9C7, Carrier-free) LS-C790935

Antibody:

WIBG Mouse anti-Human Monoclonal (Carrier-free) (OTI9C7) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

WIBG Antibody (aa12-40) LS-C326360

Antibody:

WIBG Rabbit anti-Human Polyclonal (aa12-40) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

WIBG Antibody (aa12-40, Biotin) LS-C273603

Antibody:

WIBG Rabbit anti-Human Polyclonal (aa12-40) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

WIBG Antibody (aa12-40, FITC) LS-C273604

Antibody:

WIBG Rabbit anti-Human Polyclonal (aa12-40) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

WIBG Antibody (aa12-40, APC) LS-C273602

Antibody:

WIBG Rabbit anti-Human Polyclonal (aa12-40) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

WIBG Antibody (aa12-40, PE) LS-C273606

Antibody:

WIBG Rabbit anti-Human Polyclonal (aa12-40) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

WIBG Antibody (aa12-40, Azide-free, HRP) LS-C273605

Antibody:

WIBG Rabbit anti-Human Polyclonal (aa12-40) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

WIBG Antibody (clone OTI11C5) LS-C339949

Antibody:

WIBG Mouse anti-Human Monoclonal (OTI11C5) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

WIBG Antibody (clone OTI11C5, Carrier-free) LS-C790905

Antibody:

WIBG Mouse anti-Human Monoclonal (Carrier-free) (OTI11C5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

WIBG Antibody (aa81-130) LS-C170340

Antibody:

WIBG Rabbit anti-Mouse Polyclonal (aa81-130) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

WIBG Antibody (clone OTI8D7) LS-C339991

Antibody:

WIBG Mouse anti-Human Monoclonal (OTI8D7) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Viewing 1-25 of 45 product results

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