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Anti-WEE1 Antibody (phospho-Ser53) LS-C199732

Ordering

Wt. Vol. Conc. Price
- 20 µl - $205
- 50 µl - $255
- 100 µl - $315
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular WEE1 Antibodies

Anti-WEE1 Antibody (aa202-230, AP) LS-C273571
Rabbit Polyclonal (IgG) to Human WEE1
Human
Western blot, ELISA
AP Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human WEE1
Human, Mouse, Rat
IHC - Paraffin, ELISA
Unconjugated

Details

Human WEE1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • ELISA

Specificity and Use

WEE1 antibody was raised against synthetic peptide derived from human WEE1 around the phosphorylation site of Ser53.
pSer53
WEE1 (Phospho-Ser53) Antibody detects endogenous levels of WEE1 only when phosphorylated at serine53.

Packaging

PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Store at -20°C.
For research use only.

About WEE1

P30291 NM_003390 NP_003381.1

WEE1 Antibody, Wee1 homolog Antibody, WEE1+ homolog Antibody, WEE1A Antibody, Wee1A kinase Antibody, WEE1hu Antibody, Wee1 tyrosine kinase Antibody, Wee1-like protein kinase Antibody, Wee1+ (S. pombe) homolog Antibody, WEE1 homolog (S. pombe) Antibody

Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur.

Immunohistochemistry

Immunohistochemistry
IHC of paraffin-embedded human breast carcinoma, using WEE1 (Phospho-Ser53) Antibody. The sample on the right was incubated with synthetic peptide.
 

Requested From: United States
Date Requested: 12/5/2016

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