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Anti-WEE1 Antibody (aa144-173) LS-C101210

Catalog Size Price
LS-C101210-400 400 µl Unavailable

Related Products

48 WEE1 Antibodies

Most Popular WEE1 Antibodies

Anti-WEE1 Antibody (phospho-Ser123) LS-C96996
Rabbit Polyclonal to Human WEE1
Human
IHC - Paraffin, Dot Blot
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Immunohistochemistry Image
Anti-WEE1 Antibody (aa144-173) LS-C101210
Rabbit Polyclonal to Human WEE1
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-WEE1 Antibody (C-Terminus) LS-C329106
Rabbit Polyclonal (IgG) to Human WEE1
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IHC, Western blot, ELISA
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Anti-WEE1 Antibody (Internal) LS-C329107
Rabbit Polyclonal (IgG) to Human WEE1
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Anti-WEE1 Antibody LS-C415508
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Immunohistochemistry Image

100% Guaranteed
Rabbit Polyclonal to Human WEE1
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated

Details

Human WEE1
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

LS-E9501 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C101210. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa144-173
This WEE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the Central region of human WEE1.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About WEE1

P30291 NM_003390 NP_003381.1

WEE1 Antibody, Wee1 homolog Antibody, WEE1+ homolog Antibody, WEE1A Antibody, Wee1A kinase Antibody, WEE1hu Antibody, Wee1 tyrosine kinase Antibody, Wee1-like protein kinase Antibody, Wee1+ (S. pombe) homolog Antibody, WEE1 homolog (S. pombe) Antibody

Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
WEE1 Antibody (A159) western blot of A431, Jurkat cell line lysates (35 ug/lane). The WEE1 antibody detected the WEE1 protein (arrow).

Requested From: 
Date Requested: 8/24/2017

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