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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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WDR5 Antibody (aa41‑90) LS‑C117008 Best Seller
WDR5 antibody LS-C117008 is an unconjugated rabbit polyclonal antibody to WDR5 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C117008-50
50 µg
Unavailable

Popular WDR5 Products

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Product Description

WDR5 antibody LS-C117008 is an unconjugated rabbit polyclonal antibody to WDR5 from human, mouse, rat and other species. Validated for WB.
About WDR5
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. P61964 AJ011376 CAB66159.1

WDR5 Antibody, BIG3 Antibody, BIG-3 Antibody, SWD3 Antibody, WD repeat-containing protein 5 Antibody, BMP2-induced 3-kb gene protein Antibody, WD repeat domain 5 Antibody, WD-repeat protein 5 Antibody


Specifications

Target
Human WDR5
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Chicken, Xenopus (tested or 100% immunogen sequence identity)
Predicted
Rabbit, Zebrafish, Drosophila (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
WDR5 antibody was raised against synthetic peptide located between aa41-90 of human WDR5 (Q5M786, NP_060058). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Xenopus, Beetle (100%); Orangutan, Rabbit, Stickleback, Zebrafish, Drosophila (92%); Sea squirt (85%).
Blocking Peptide
LS-E15192 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C117008. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa41-90
Specificity
Human WDR5
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

WDR5 antibody LS-C117008 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
WDR5 antibody LS-C117008 Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

WDR5 antibody LS-C117008 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
WDR5 antibody LS-C117008 Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

WDR5 antibody LS-C117008 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
WDR5 antibody LS-C117008 Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

WDR5 antibody LS-C117008 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
WDR5 antibody LS-C117008 Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/18/2018

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