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Anti-VWF / Von Willebrand Factor Antibody (aa1498-1665, clone 210905) LS-C150102

Ordering

Wt. Vol. Conc. Price
500 µg - - $680
Inquire for larger quantities

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Most Popular VWF / Von Willebrand Factor Antibodies

Anti-VWF / Von Willebrand Factor Antibody (N-Terminus, clone VW92-3) LS-C83336
Mouse Monoclonal [clone VW92-3] (IgG2a) to Human VWF / Von Willebrand Factor
Human
IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Unconjugated
Anti-VWF / Von Willebrand Factor Antibody IHC-plus™ LS-B2590
Goat Polyclonal (IgG) to Human VWF / Von Willebrand Factor
Human
IHC - Paraffin, ELISA, Immunoelectrophoresis
Unconjugated
Immunohistochemistry Image

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Mouse Monoclonal [clone 210905] (IgG2b) to Human VWF / Von Willebrand Factor
Human
ICC, Western blot, Immunoprecipitation
Unconjugated

Details

Human VWF / Von Willebrand Factor
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [210905]
Unconjugated
Protein A/G purified
Unmodified

Applications

  • ICC (8 - 25 µg/ml)
  • Western blot (1 µg/ml)
  • Immunoprecipitation (25 µg/ml)

Specificity and Use

VWF / Von Willebrand Factor antibody was raised against e. coli-derived recombinant human vWFA2 Asp1498-Val1665 Accession # P04275.
aa1498-1665
Detects human vWFA2 in direct ELISAs and Western blots. Detects an epitope N-terminal to the ADAMTS13 cleavage site between.
Western Blot, 1 µg/ml, Recombinant Human vWF-A2. Immunocytochemistry, 8-25 µg/ml. Immunoprecipitation, 25 µg/ml, Cell lysates spiked with Recombinant Human vWF-A2.

Packaging

Lyophilized from 0.2 um filtered solution in PBS, trehalose
Sterile PBS. Resuspend to 1 ml
Store at -20°C. After reconstitution, aliquot and store at -20°C. Avoid freeze/thaw cycles.
For research use only.

About VWF / Von Willebrand Factor

P04275 NM_000552 NP_000543.2

VWF Antibody, Coagulation factor VIII VWF Antibody, F8VWF Antibody, VWD Antibody, Von Willebrand factor Antibody

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

Immunocytochemistry

Immunocytochemistry
vWF-A2 in HUVEC Human Cells. vWF-A2 was detected in immersion fixed HUVEC human umbilical vein endothelial cells using Mouse Anti-Human vWF-A2 Monoclonal Antibody at 10 ug/ml for 3 hours at room temperature. Cells were stained using NorthernLights 557-conjugated Anti-Mouse IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm.
 

Requested From: United States
Date Requested: 12/8/2016

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